Rezvan Yazdian-Robati
Department of Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
[ 1 ] - Recognition and characterization of Erythropoietin binding-proteins in the brain of mice
Objective(s): Erythropoietin (EPO), is a 34KDa glycoprotein hormone, which belongs to type 1 cytokine superfamily. EPO involves in erythrocyte maturation through inhibition of apoptosis in erythroid cells. Besides its main function, protective effects of EPO in heart and brain tissues have been reported. EPO has a critical role in development, growth, and homeostasis of brain. Furthermore EPO h...
[ 2 ] - Colorimetric gold nanoparticles-based aptasensors
Recognition of different agents including chemical and biological plays important role in forensic, biomedical and environmentalfield.In recent decades, nanotechnology and nano materials had a high impact on development of sensors. Using nanomaterials in construction of biosensors can effectively improve the Sensitivity and other features of biosensors. Different type of nanostructures includi...
[ 3 ] - Anti-melanogenic activity of different extracts from aerial parts of Nepeta glomeruloasin on murine melanoma B16F10 cells
Nepeta glomerulosa Boiss. is a medicinal plant has been used in traditional medicine. The aim of this study was to evaluate the anti-melanogenesis inhibitory activity of MeOH, n-hexane, ethyl Acetate (EtAc), dichloromethane (CH2Cl2), n-butanol (BuOH) and H2O extracts isolated from N. glomerulosa in B16 melanoma cell line. The B16F10 cell line viability after treatment with increasing concentrat...
[ 4 ] - Evaluation of Neuroprotective Effect of Althaea Officinalis Flower Aqueous and Methanolic Extracts against H2O2-Induced Oxidative Stress in PC12 Cells
Objective: This study was conducted to evaluate the possible antioxidant activity and neuroprotective effects of aqueous and methanolic extracts of Althaea officinalis flowers against H2O2-induced oxidative stress in PC12 cells. Material and Methods: The antioxidant potential of extracts was evaluated by radical scavenging activity using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay. For c...
[ 5 ] - The mechanism of neuroprotective effect of Viola odorata against serum/glucose deprivation-induced PC12 cell death
Objective: Oxidative stress is associated with the pathogenesis of brain ischemia and other neurodegenerative disorders. Previous researches have shown the antioxidant activity of Viola odorata L. In this project, we studied neuro-protective and reactive oxygen species (ROS) scavenging activities of methanol (MeOH) extract and other fractions isolated from <e...
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