Shiva Roshankhah
Department of Anatomical Sciences, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran
[ 1 ] - An animal model study for bone repair with encapsulated differentiated osteoblasts from adipose-derived stem cells in alginate
Objective(s): Adipose derived stem cells (ADSCs) can be engineered to express bone specific markers. The aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous ADSCs in alginate scaffold. Materials and Methods: In this study, 6 canine’s ADSCs were encapsulated in alginate and differentiated into osteoblasts. Alkaline phosphatase assay (A...
[ 2 ] - The effect of high frequency electric field on enhancement of chondrogenesis in human adipose-derived stem cells
Objective(s):Osteoarthritis (OA) is globally one of the most common diseases from the middle age onwards. Cartilage is an avascular tissue therefore it cannot be repaired in the body. Conservative treatments have failed as a good remedy and cell therapy as a decisive cure is needed. One of the best and easily accessible cell sources for this purpose is adipose-derived stem cells which can be di...
[ 3 ] - The effects of Petroselinum crispum extract on milk production parameters in female rats
Background and Aim: Use of medicinal plants is one of the methods to increase breast milk. Petroselinum crispum is a multipurpose herb in traditional medicine which contains essential amino acids, vitamins and numerous nutrients. This study aimed to determine the effects of Petroselinum crispum extract on milk production parameters in female rats. Material and Methods: In this experimental stud...
[ 4 ] - Crocin Reduces Oxidative Stress Produced by Busulfan Administration on Fertility of Male Rats
Background & Objective: Busulfan (BUS) as a drug for cancer treatment can produce free radicals. Crocin (CRO) is a potent antioxidant with beneficial effects. This study was designed to evaluate the effects of CRO against BUS-related damages to the male rats reproductive parameters. Materials & Methods: Forty-eight male rats were randomly assigned into 8 groups; Group 1 (normal control group) ...
[ 5 ] - Harmine recover kidney damage induced by morphine in male rats
Harmine is a harmal-derived alkaloid with antioxidant properties. The morphine produces free radicals and plays a key role in the pathogenesis of kidney disease. This study was designed to evaluate the effects of harmine against morphine- induced damage to the kidneys of rats. In this study, 64 male rats were randomly assigned to 8 groups: saline and morphine treated groups; harmine groups (5, ...
[ 6 ] - Sambucus Nigra Synergizes Cisplatin to Improve Apoptosis and Metabolic Disorders, and Reduce Drug Resistance in Two Human Breast Cancer Cell Lines
Background: Despite modern developments in its management, still major concerns remain about drug resistance in chemotherapy. Natural adjuvants combined with chemotherapy might be the answer. We examined the anti-cancer, anti-proliferative and synergistic effects of Sambucus nigra extract with cisplatin chemotherapy (CDDP) on MCF-7 and MDA-MB-231 human cancer cell lines. Methods: MCF-7 and MDA...
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