Mohammadreza Abbaspour

Targeted Drug Delivery Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

[ 1 ] - Anticancer Activity of Curcumin-Loaded PLGA Nanoparticles on PC3 Prostate Cancer Cells

Curcumin (Cur) has been found to be very efficacious against many different types of cancercells. However, the major disadvantage associated with the use of Cur is its low systemicbioavailability. Our present work investigated the toxic effect of encapsulation of Cur in PLGA(poly lactic-coglycolic acid) nanospheres (NCur) on PC3 human cancer prostate cell. In thepresent study, we have investiga...

[ 2 ] - Anticancer Activity of Curcumin-Loaded PLGA Nanoparticles on PC3 Prostate Cancer Cells

Curcumin (Cur) has been found to be very efficacious against many different types of cancercells. However, the major disadvantage associated with the use of Cur is its low systemicbioavailability. Our present work investigated the toxic effect of encapsulation of Cur in PLGA(poly lactic-coglycolic acid) nanospheres (NCur) on PC3 human cancer prostate cell. In thepresent study, we have investiga...

[ 3 ] - Formulation and optimization of a new cationic lipid-modified PLGA nanoparticle as delivery system for Mycobacterium tuberculosis HspX/EsxS fusion protein: An experimental design

Polymeric particles and liposomes are efficient tools to overcome the low immunogenicity of subunit vaccines. The aim of the present study was formulation and optimization of a new cationic lipid-modified PLGA nanoparticles (NPs) as a delivery system for Mycobacterium tuberculosis HspX/EsxS fusion protein. The cationic lipid-modified PLGA NPs containing HspX/EsxS fusion protein were prepared us...

[ 4 ] - Formulation and optimization of a new cationic lipid-modified PLGA nanoparticle as delivery system for Mycobacterium tuberculosis HspX/EsxS fusion protein: An experimental design

Polymeric particles and liposomes are efficient tools to overcome the low immunogenicity of subunit vaccines. The aim of the present study was formulation and optimization of a new cationic lipid-modified PLGA nanoparticles (NPs) as a delivery system for Mycobacterium tuberculosis HspX/EsxS fusion protein. The cationic lipid-modified PLGA NPs containing HspX/EsxS fusion protein were prepared us...