Khalil Mahmoodi

Department of Cardiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

[ 1 ] - A preliminary study of the association between the ABCA1 gene promoter DNA methylation and coronary artery disease risk

Coronary artery disease (CAD) is a common health problem in Iranian population. ATP binding cassette transporter A1 (ABCA1) plays central role in the efflux of the cholesterol from peripheral tissues back to liver. Inactivation of ABCA1 by epigenetic change such as DNA methylation may contribute to the development of CAD. The present study investigated the association between promoter DNA methy...

[ 2 ] - The association between NFKB1 -94ATTG ins/del and NFKB1A -826C/T genetic variations and coronary artery disease risk

Coronary artery disease (CAD) is considered as a chronic inflammatory disease initiated from early childhood. Nuclear factor κB (NF κB) and κB1A (NF κB1A) are the key regulators of inflammatory responses. The NFKB1 -94ATTG ins/del and NFKB1A -826C/T polymorphisms may contribute to the development of CAD.  The aim of the present study was to investigate the association of these polymorphisms wit...

نویسندگان همکار