آهنجان, محمد
دانشیار، گروه میکروبشناسی، مرکز تحقیقات عفونی اطفال، دانشگاه علوم پزشکی مازندران، ساری، ایران
[ 1 ] - بررسی فنوتیپی باکتری های مولد UTI و الگوی مقاومت آنتی بیوتیکی در افراد دیابتی
Background and purpose: Urinary tract infections (UTI) are one of the most common complications of diabetes. Asymptomatic bacteriuria or frequent symptomatic urinary tract infection are common in diabetic patients. Study of bacterial factors of UTI in these patients and the antibiotic resistance pattern and resistant strains are necessary. Materials and methods: In this descriptive cross-s...
[ 2 ] - بررسی مقاومت آنتی بیوتیکی و شیوع ژن های بتالاکتامازی کلبسیلا پنومونیه در بیمارستان های آموزشی دانشگاه علوم پزشکی مازندران 1393
Background and purpose: : Klebsiella pneumoniae has emerged as a significant opportunistic pathogen responsible for nosocomial infections. This bacteria is frequently resistant to multiple classes of antibiotics such as family of beta-lactam antibiotics. β-lactamases enzyme represent the main mechanism of bacterial resistance to β-lactam antibiotics. This study was conducted to determi...
[ 3 ] - بررسی ژن مقاومت بتالاکتاماز CTX در اشرشیا کلی جدا شده از نمونه های عفونت ادراری بیمارستان های آموزشی دانشگاه علوم پزشکی مازندران به روش واکنش زنجیره ای پلیمراز (PCR)
Abstract Background and purpose: Escherichia Coli is one of the most common pathogens associated with nosocomial infection. Increasing use of beta Lactam Antibiotics in treatment of bacterial infections resulted in increments of drug resistance of such bacteria that is caused due to the production of B-lactamase enzymes. The beta lactamase – producing bacteria especially E.coli which is resi...
[ 4 ] - شیوع مقاومت آنتی بیوتیکی استافیلوکوک اورئوس مقاوم به متی سیلین و تعیین ژن مقاومت به آمینوگلیکوزید به روش PCR در بیمارستان های ساری و تهران
Abstract Background and purpose: Staphylococcus aureus is one of the major causes of community and hospital-acquired infections. Aminoglycosides are potent bactericidal agents that are often used in combination with beta-lactam or glycopeptide in treatment of staphylococcal infections. The aim of this study was to investigate the prevalence of the aminoglycoside modifying enzyme aac(6΄)-Ie/aph(...
[ 5 ] - فراوانی استافیلوکوکوس اورئوس جدا شده مقاوم به متی‌سیلین از دست و بینی کارکنان مراکز آموزشی - درمانی شهر ساری (1391)
زمینه و هدف : استافیلوکوکوس اورئوس مقاوم به متی‌سیلین از پاتوژن‌های مهم بیمارستانی است. این مطالعه به منظور تعیین فراوانی استافیلوکوکوس اورئوس جدا شده مقاوم به متی‌سیلین از دست و بینی کارکنان مراکز آموزشی - درمانی شهر ساری انجام شد. روش بررسی : این مطالعه توصیفی روی 148 نفر از کارکنان درمانی بخش‌های مختلف بیمارستان‌های آموزشی شهرستان ساری در سال 1391 انجام شد. از انگشتان دست و ناحیه قدامی بینی...
[ 6 ] - بررسی موتاسیون در ژن gyrAدر سویه های بالینی اشریشیا کلی و کلبسیلا پنومونیه جدا شده ازبیمارستان امام خمینی(ره) شهرستان ساری
Background and purpose: Increasing resistance to Quinolones in Escherichia coli and Klebsiella pneumonia in Sari, has caused many problems in treatment. Mutation in gyrA gene lead to changes in amino acids and resistance against Fluoroquinolones in E. coli and K. pneumonia. This study aimed at identifying remarkable mutations in E. coli and K. pneumonia isolates using PCR-SSCP analysis. Materi...
[ 7 ] - تشخیص عفونت هلیکوباکترپیلوری در بیماران مبتلا به زخم معده با استفاده از آزمایش‌های سرولوژی و آنتی‌ژن مدفوعی
ABSTRACT Background & Objectives: Helicobacter pylori is a gram negative, microaerophilic and flagellated bacillus, which causes digestive diseases, such as peptic ulcer and gastric cancer. This study aimed to detect Helicobacter pylori in patients with ulcer disease through stool antigen and serological tests in Sari, Iran. Materials and Methods: In this study, 120 patients (aged 15-66 yea...
[ 8 ] - Evaluation of Bacterial Contamination in Clinical Environment of Sari Dental School in 2018
Background and Aim: Bacterial contamination of clinical surfaces of dental units that have been touched or been exposed to patients’ blood or saliva can be a reservoir for infections, leading to cross-contamination. This study aimed to evaluate bacterial contamination in the clinical environment of Sari Dental School in 2018. Materials and Methods: In this cross-sectional (descriptive-analytic...
[ 9 ] - Comparing the Effect of Probiotic and Non-probiotic Yogurt Drinks on Two Common Oral Microorganisms: An In Vitro Study
Background and purpose: Decrease in the number of oral microorganisms leads to reduction in caries score. Bacterial therapy, such as using probiotic bacteria, is an alternative procedure in treatment of infections caused by microorganisms. The purpose of this study was to compare the effect of probiotic and non-probiotic yogurt-drink on two common oral microorganisms. Materials and methods: In...
[ 10 ] - Green Synthesis of Silver Nanoparticles with Allium paradoxum Extract and Evaluation of their Antibacterial Activities
Background and purpose: Microbial resistance against antibiotics is increasingly growing, therefore, it is necessary to develop new remedies. Silver nanoparticles have significant antibacterial properties and synthesis of silver nanoparticles mediated by plant extracts could be considered as an alternative in treatment in various infections. Materials and methods: In this study, silver nano...
[ 11 ] - Evaluation of Cell Growth Inhibition of Bifidobacterium Bifidum Cell-free Supernatant Extract on 4T1Tumor Cell Lineage
Background: Cancer is amongst the leading reasons of death in all parts of the world. Breast cancer is also responsible for the largest number of deaths among women population. Several studies confirmed that Bifidobacterium bifidum as a probiotic meaningfully inhibited breast cancer development. The present study aimed to investigate the effect of B. bifidum supernatant on the cell growth inhib...
[ 12 ] - Molecular Identification of ESBLs Genes (blaTEM, blaSHV and blaCTX) among Non-fermenting Gram-negative Bacteria Isolated from Hospitalized Patients in Mazandaran Province, Iran
Background and purpose: Production of beta-lactamase enzymes by bacteria, especially Extended-spectrum β-lactamases (ESBLs) is one of the major problems worldwide. ESBLs are mostly located on bacterial plasmids and it is recognized that SHV, TEM, and CTX-M are prevailing among them. The aim of this study was to determine the ability to produce ESBLs genes based on molecular method among non-fer...
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