Mohammad Ali Ebrahimzadeh
Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - Hypothermic activity of acetaminophen; Involvement of GABAA receptor, theoretical and experimental studies
Objective(s):The mechanism of hypothermia action of acetaminophen (APAP) remains unclear even 125 years after its synthesis. Acetaminophen produces hypothermia. The mechanism of this reduction in core body temperature is not clear but evidence shows that it is not dependent on opioid and cannabinoid receptors. Because of strong documents about the roles of GABA and benzodiazepine receptors in h...
[ 2 ] - Correlation Between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of Some Medicinal Plants
Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing skin problems. Skin protection is a suitable method in the fight against ultraviolet radiation induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they h...
[ 3 ] - Treatment of Paederus Dermatitis with Sambucus ebulus Lotion
AbstractPaederus dermatitis is an irritant contact dermatitis due to accidental contact by a beetle belonging to the genus paederus. In this study, clinical efficacies of S. ebulus fruit extract solution in patients affected by paederus dermatitis were evaluated. A randomized double-blind, prospective, placebo-controlled clinical trial was performed in 62 patients with clinical symptoms and sin...
[ 4 ] - Correlation Between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of Some Medicinal Plants
Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing skin problems. Skin protection is a suitable method in the fight against ultraviolet radiation induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they h...
[ 5 ] - Treatment of Paederus Dermatitis with Sambucus ebulus Lotion
AbstractPaederus dermatitis is an irritant contact dermatitis due to accidental contact by a beetle belonging to the genus paederus. In this study, clinical efficacies of S. ebulus fruit extract solution in patients affected by paederus dermatitis were evaluated. A randomized double-blind, prospective, placebo-controlled clinical trial was performed in 62 patients with clinical symptoms and sin...
[ 6 ] - تاثیر روش های مختلف استخراج بر فعالیت آنتی اکسیدانی و فعالیت آنتی باکتریال گیاه Nonnea lutea
Background and purpose: No reports are found on biological activities of Nonea lutea (boraginaceae). The aim of this study was to investigate the antioxidant and antibacterial activities of this plant. Materials and methods: The aerial parts were extracted by three different methods, i.e. meceration (MA), ultrasonic assisted (US), and soxhlet assisted (SO) extractions with methanol. Antioxidat...
[ 7 ] - ارزیابی فعالیت آنتی اکسیدانی ماشک معمولی(Vicia hirsuta)، اهمیت روش استخراج
Background and purpose: The genus Vicia (Papilionaceae) contains 45 species in Iran. This investigation was designed to study the impact of extraction methods on total phenolic and flavonoid contents and antioxidant activities of V. hirsuta aerial parts. Materials and methods: In this experimental study the efficiencies of three extraction methods i.e. Maceration, Soxhlet, and ultrasonically a...
[ 8 ] - Protective effects of methanolic extract of Vicia cracca against hypoxia-induced lethality in mice
Vicia genus has 45 species in Iran. Many protective and biological activities have been reported from these species. In spite of many works, nothing is known about protective effect of V. cracca against hypoxia conditions. In this study, protective effects of V. cracca extract against hypoxia-induced lethality in mice were evaluated by three experimental models of hypoxia, asphyctic, haem...
[ 9 ] - بررسی فعالیت آنتی اکسیدانی در سه رقم برنج
Background and purpose: Rice (Oryzasativa L.) is one the most important staple food in the world. There is an increasing interest for pigmented varieties, due to their antioxidant properties. In this research, the antioxidant activities in different parts of three varieties of rice were studied. Materials and methods: White rice, brown rice, husk, and bran of Fajr, Hashemi and KB13 were extrac...
[ 10 ] - Safety Evaluation of Nano Iron Zero Valente Green Synthesized: A Comparative Study
Objective(s): Nowadays, examining the toxicity of nanoparticles including the synthesized and functionalized iron nanoparticles using methods like green synthesis is highly considered, due to their increasing usage in various fields of medicine, biology, industrial, and pollution removal. Hence, in this study, the toxicity of the zero valent iron nanoparticles synthesized by plant-Myrtus commun...
[ 11 ] - Green synthesis of multifunctional silver nanoparticles using quercetin and their therapeutic potential
Objective(s): Active species used in bio-chemical for synthesizing nanoparticles is poly phenolic compounds. The ability of flavonoids (e.g. quercetin) to dissolve in water is low and the production of metallic nanoparticles from them in the aqueous medium is hard. Previous studies recommend that quercetin was not capable of reducing Ag+ to Ag0. The current research aimed at synthesizing querce...
[ 12 ] - Green Synthesis of Silver Nanoparticles with Allium paradoxum Extract and Evaluation of their Antibacterial Activities
Background and purpose: Microbial resistance against antibiotics is increasingly growing, therefore, it is necessary to develop new remedies. Silver nanoparticles have significant antibacterial properties and synthesis of silver nanoparticles mediated by plant extracts could be considered as an alternative in treatment in various infections. Materials and methods: In this study, silver nano...
[ 13 ] - Stereological and Molecular Studies on the Effects of Echinopsis chamaecereus Extract on Wound Healing in Rats
Background and purpose: Effective medicines, especially herbal products, have received a lot of interest in recent years. The purpose of this study was to investigate the wound healing effect of Echinopsis chamaecereus extract ointment that has high antioxidant power in the healing of full-thickness skin wounds in rats. Materials and methods: In this experimental study, 50 male rats were rand...
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