پوریای ولی, محمد حسن

[ 1 ] - مقایسه علائم بالینی، یافته‌های آزمایشگاهی و دموگرافیک در کودکان مبتلا به عفونت حاد دستگاه تنفس تحتانی با ویروس سنسیشیال تنفسی و متاپنوموویروس انسانی

Background: There is a large overlap among various etiologic agents of lower respiratory tract infections (LRTI). Human metapneumovirus (hMPV) is a novel agent which could cause a similar clinical picture as RSV which necessitate more evaluation in developing countries Methods: In this cross sectional study, pharyngeal swabs from admitted kids with LRTI under 5 years of age were analyzied by...

[ 2 ] - A Case of Methotrexate Intoxication Misdiagnosed as Crimean-Congo Hemorrhagic Fever

[No Abstract] Crimean-Congo hemorrhagic fever (CCHF) is considered as the most important arboviral infection in Iran. Early diagnosis of CCHF is essential for preventing the spread of the infection and providing appropriate treatment to patients. Given that clinical symptoms of CCHF may overlap with other common infectious disease; differential diagnosis is a matter of great importance. In this...

[ 3 ] - Establishment of NS3 tumor cell line expressing Hepatitis C virus Non-structural Protein 3 as valuable tool for HCV challenging in mice

Introduction: Hepatitis C virus (HCV) is one of the major medical problems. Human and chimpanzees are the only specific hosts which are naturally susceptible to HCV infection. Mice and other common laboratory animals are resistant to the virus, hence HCV prophylactic and therapeutic researches are very difficult and challenging. HCV non-structural protein 3 (NS3) is one of the most attractive t...

[ 4 ] - Construction of pIRES2 vector encoding truncated NS3 of HCV and IL-18 for DNA vaccine studies

Introduction: Long term complications of hepatitis C virus (HCV) infection include fibrosis, cirrhosis, and hepatocellular carcinoma and although the disease is treatable with the newly introduced direct acting antivirals, but factors such as drug resistance, viral genotype and adverse effects can limit the effectiveness of therapy. Therefore, development of effective, safe and affordable proph...

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