Shahidi, Maryam
Department of Biochemistry and Biophysics, Faculty of Medicine, Mazandaran University of Medical Sciences, Mazandaran, Sari, Iran
[ 1 ] - An Increased Genotoxic Risk in Lymphocytes from Phototherapy-Treated Hyperbilirubinemic Neonates
Background: Phototherapy is believed to be a safe method for the management of hyperbilirubinemia. However, there are some controversial issues regarding the genotoxic effects of phototherapy on DNA. The aim of this study was to investigate morphologically both phototherapy-induced DNA double-strand breaks (DSBs) and apoptosis in lymphocytes derived from jaundiced and non-jaundiced neonates. Me...
[ 2 ] - Interindividual differences in radiation-induced apoptosis of peripheral blood leukocytes in normal individuals and breast cancer patients
Background: Quantification of radiation-induced apoptosis in peripheral blood lymphocytes (PBLs) has been proposed as a possible screening test for cancer-prone individuals and also for the prediction of normal tissue responses after radiotherapy. Materials and Methods: The neutral version of the comet assay (single-cell gel electrophoresis) was used 24, 48, 72 hours after irradiation ...
[ 3 ] - Dosimetric Evaluation of Target Volume in Breast Boost Radiotherapy: Comparison of Electron and Photon Beam
Background and purpose: Breast‑conserving surgery followed by radiation therapy to the whole breast is now recognized as a standard strategy in patients with breast cancer. Recommended technique for radiotherapy is whole breast irradiation followed by boost to the tumor bed. This study aimed to compare the dosimetric parameters of electron and photon beams for boosting irradiation in post‑lump...
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