Reza Mirfakhraie
Department of Medical Genetics, Faculty of Medicine, ShahidBeheshtiUniversity of Medical Sciences,Tehran, Iran.
[ 1 ] - Evaluation of Placentalmir-155-5p and Long Non-coding RNA sONE Expression in Patients with Severe Pre-eclampsia
It has been well documented that preeclampsia (PE) has a common etiological background, but little is known about its linkage at the molecular level.Non- coding RNAs are critical posttranscriptional regulators ofgene expression. This study was performed to determine whether PEis associated with alterations in placental non-codingRNAs expression. MicroRNA(miR)-155-5p and long non-coding RN...
[ 2 ] - Association Study of rs3184504 C>T Polymorphism in Patients With Coronary Artery Disease
Cardiovascular disease has become the main factor of death and birth defects in the world and also in Iran. New clinical studies have shown that early diagnosis of patients with coronary artery disease (CAD) can contribute to effective prevention or therapeutic structures, which reduce mortality or the next chance of cardiovascular events, and increase the quality of life. Most studies on CAD d...
[ 3 ] - HIWI2 rs508485 Polymorphism Is Associated with Non-obstructive Azoospermia in Iranian Patients
Background: The PIWI-interacting RNA (piRNA) pathway has an essential role in transposon silencing, meiosis progression, spermatogenesis, and germline maintenance. HIWI genes are critical for piRNA biogenesis and function. Therefore, polymorphisms in HIWI genes contribute to spermatogenesis defects and can be considered as risk factors for male infertility. The aim of the present study was to i...
[ 4 ] - Investigation of the Association between Rs13075270 and Rs13092160 Polymorphisms of CCR1 and CCR3 Genes with Behcet’s Disease
Introduction: Behcet's disease is an autoimmune disease that can affect various parts of the body. This disease manifests itself with skin, oral and ocular lesions. Although it is an idiopathic disease, various factors, including environmental and genetic factors, contribute to the onset of it. In this study, the association between two polymorphisms, namely rs13075270 and rs13092160 of CCR1 an...
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