Sara Hosseinian
Department of physiology, School of medicine, Mashhad University of Medical Sciences, Mashhad, Iran
[ 1 ] - Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major
Objective: The aim of the present study was to evaluate the possible protective effect of Plantago major (P. major) extract against doxorubicin (DXR)-induced renal inflammation in rats. Materials and Methods: 80 male albino rats were randomly divided into 8 groups as follows: control, DXR, Ext (extract) 600, Ext1200, dexamethasone+DXR, vitamin E+DXR, Ext600+DXR, and Ext1200+DXR. Duration of the...
[ 2 ] - The protective effect of Nigella sativa against cisplatin-induced nephrotoxicity in rats
Objective: The clinical use of cisplatin is highly restricted, because of its nephrotoxicity.In this study the protective effect of Nigella sativa (N. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. Materials and Methods: In the current study, the effects of the administration of aqueous-ethanolic extract of N. sativa (100 and 200 mg/kg, BW) and vitamin E (100 mg/kg, ...
[ 3 ] - Adriamycin-induced oxidative stress is prevented by mixed hydro-alcoholic extract of Nigella sativa and Curcuma longa in rat kidney
Objective: Inflammation and oxidative stress is considered to have a crucial role in induction of nephropathy. Curcuma longa (C. longa) and Nigella sativa (N. sativa) have anti-inflammatory and antioxidant effects. This study was designed to investigate the effect of mixed hydro-alcoholic extract of N.sativa and C. longa on the oxidative stress induced by Adriamycin (ADR) in rat kidney. Materia...
[ 4 ] - Effect of commercial (vimang) and hydroalcoholic extract of Mangifera indica (Mango) on gentamicin-induced nephrotoxicity in rat
Objectives: Mangifera indica (Mango) is used in folk medicine for treatment of different types of diseases, and its anti-inflammatory and free radical scavenging activities have been demonstrated. The present study evaluated the effects of commercial (vimang) and hydroalcoholic extract of Mango on gentamicin-induced nephrotoxicity in rat. Materials and Methods: Female Wistar rats were treated ...
[ 5 ] - The role of Artemisia turanica extract on renal oxidative and biochemical markers in STZ-induced diabetes in rat
Objective: The aim of the current study was to investigate the protective effect of Artemisia turanica (AT) against diabetes- induced renal oxidative stress in rats. Materials and Methods: Fifty male Wistar rats were randomly divided into five groups: control, STZ-induced diabetic rats, diabetic rats+ metformin, diabetic rats + AT extract, diabet...
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