Shahrzad Havakhah
Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
[ 1 ] - The protective effect of Nigella sativa against cisplatin-induced nephrotoxicity in rats
Objective: The clinical use of cisplatin is highly restricted, because of its nephrotoxicity.In this study the protective effect of Nigella sativa (N. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. Materials and Methods: In the current study, the effects of the administration of aqueous-ethanolic extract of N. sativa (100 and 200 mg/kg, BW) and vitamin E (100 mg/kg, ...
[ 2 ] - Effect of commercial (vimang) and hydroalcoholic extract of Mangifera indica (Mango) on gentamicin-induced nephrotoxicity in rat
Objectives: Mangifera indica (Mango) is used in folk medicine for treatment of different types of diseases, and its anti-inflammatory and free radical scavenging activities have been demonstrated. The present study evaluated the effects of commercial (vimang) and hydroalcoholic extract of Mango on gentamicin-induced nephrotoxicity in rat. Materials and Methods: Female Wistar rats were treated ...
[ 3 ] - Effect of Nigella sativa on ischemia-reperfusion induced rat kidney damage
Objective(s):There are a few previously reported studies about the effect of Nigella sativa oil on renal ischemia-reperfusion injury (IRI). The aim of the present study was to test the hypothesis whether pre- or post-treatment with N. sativa hydroalcoholic extract (NSE) would reduce tissue injury and oxidative damages in a clinically relevant rat model of renal IRI. Materials and Methods: IR...
[ 4 ] - The evaluation and comparing of cytotoxic effects of Ferula gummosa gum, Scutellaria lindbergii, Kelussia odoratissima and Artemisia kopetdaghensis extracts on ACHN cell line
Renal cell carcinoma (RCC) is one of most fatal cancers. In most patients It is resistant to chemotherapy. Ferula gummosa gum, Scutellaria lindbergii, Kelussia odoratissima and Artemisia kopetdaghensis are herbs that there are some cytotoxic activity reports about them. In this study cytotoxic and apoptotic activity of these four extracts on RCC cell line (ACHN) were evaluated and compared.ACHN...
[ 5 ] - The evaluation and comparing of cytotoxic effects of Ferula gummosa gum, Scutellaria lindbergii, Kelussia odoratissima and Artemisia kopetdaghensis extracts on ACHN cell line
Renal cell carcinoma (RCC) is one of most fatal cancers. In most patients It is resistant to chemotherapy. Ferula gummosa gum, Scutellaria lindbergii, Kelussia odoratissima and Artemisia kopetdaghensis are herbs that there are some cytotoxic activity reports about them. In this study cytotoxic and apoptotic activity of these four extracts on RCC cell line (ACHN) were evaluated and compared.ACHN...