STRESZCZENIE Wstęp. Skład ma sy cia ła zmie nia się w okre sie roz wo jo wym i jest zna czą co ró żny u dzie ci ze sko lio zą idio pa tycz ną (SI). Ce lem ba da nia by ła oce na stop nia odży wie nia pa cjen tów z SI w opar ciu o stan dar do we po mia ry an tro po me trycz ne oraz me to dę bio im pe dan cji (BIA). Ma te riał i me to dy. Gru pę ba da ną sta no wi ło 59 cho rych z SI (45 dziew cz...

We have proposed that steatohepatitis results from reactive oxygen species (ROS) acting on accumulated fatty acids to form proinflammatory lipoperoxides. Cytochrome P450 4a (Cyp4a) and Cyp2e1 are potential hepatic sources of ROS. We tested the hypothesis that increasing Cyp4a through activation of peroxisome proliferator-activated receptor alpha (PPARalpha) should aggravate steatohepatitis prod...

BACKGROUND Graft choice for anterior cruciate ligament (ACL) reconstruction is of critical importance. Various grafts have been used so far, with autografts long considered the optimal solution for the treatment of ACL-deficient knees. Limited data are available on the long-term survivorship of synthetic grafts. PURPOSE To compare the functional outcome and survivorship of ACL reconstructions...

There are errors in the values for LARS for thyroid cancer throughout the paper. Please see below for a description of the errors and their corrections. There are errors in the last two sentences of the Abstract. The correct sentences are: Lifetime attributable risks (LARs) of thyroid cancers due to ingestion were 1.7–37×10 (Case 1) and 5.6–79×10 (Case 2) in Fukushima City, 0.73–13×10 in Tokyo,...

The peroxisome proliferator activated receptor-α (PPARα) is a major transcriptional regulator of lipid metabolism in liver and represents the molecular target for hypolipidemic fibrate drugs. Effects of PPARα on lipid metabolism are partially mediated by circulating proteins such as FGF21 and ANGPTL4. The present study was undertaken to screen for and identify circulating proteins produced by h...

OBJECTIVES To investigate how bowel dysfunction after sphincter-preserving rectal cancer treatment, known as low anterior resection syndrome (LARS), is perceived by rectal cancer specialists, in relation to the patient's experience. DESIGN Questionnaire study. SETTING International. PARTICIPANTS 58 rectal cancer specialists (45 colorectal surgeons and 13 radiation oncologists). RESEARCH...

Essential amino acids (EAAs) are potent stimulators of mechanistic target of rapamycin complex 1 (mTORC1) signaling and muscle protein synthesis. However, regulators upstream of mTORC1 that are responsive to EAA availability are not well described, especially in human skeletal muscle. The purpose of this study was to determine changes in leucyl-tRNA synthetase (LARS/LARS) and Ras-related GTP bi...