OBJECTIVE Vascular progenitors of bone marrow origin participate to neovascularization at sites of wound healing and transplantation. We hypothesized that the biological purpose of this bone marrow-derived vascular component is to contribute angiogenic and survival functions distinct from those provided by the local tissue-derived vasculature. RESEARCH DESIGN AND METHODS AND RESULTS To addres...

OBJECTIVE To analyze the spirometry findings in patients undergoing bone marrow transplant, determining the importance of such findings in predicting postoperative pulmonary complications and looking for correlations with postoperative outcomes. METHODS The spirometry findings in 120 male and female patients, all above the age of 12, were evaluated retrospectively and compared in terms of the...

Abstract After a bone marrow transplant between siblings, another family members’ cells live on in the recipient’s body. This connects members variety of ways. Some families saw it as an essential change body and identity, while others unification two separate individuals. described donor’s “spare parts depot”; being seen life-saving resource then created lasting responsibility donors. relation...

Stem cells can differentiate into a variety of cells to replace dead cells or to repair damaged tissues. Recent evidence indicates that stem cells are involved in the pathogenesis of transplant arteriosclerosis, an alloimmune initiated vascular stenosis that often results in transplant organ failure. Although the pathogenesis of transplant arteriosclerosis is not yet fully understood, recent de...

8 Reiffers J, Goldman J, Meloni G, Cahn JY, Gratwohl A. Autologous stem cell transplantation in chronic myelogenous leukaemia: A retrospective analysis of the European Group of Bone Marrow Transplantation. Bone Marrow Transplanl1994; 14:407-10. 9 Coulombel L, Kalousek DK, Eaves CJ, Gupta CM, Eaves AC. Long term marrow culture reveals chromosomally normal haematopoietic progenitor cells in patie...

Background: Myelodysplastic syndrome with co-existing bone marrow fibrosis is associated with a dismal prognosis with conventional therapy. Allogeneic hematopoietic stem cell transplant (HSCT) offers the sole treatment approach that offers curative potential. HSCT has been utilized in younger patients with this disorder however with the advent of reduced intensity conditioning (RIC) regimens it...

introduction: the use of cord stem cells, as a cell source for bone marrow reconstruction in patient under hematopoietic stem cell transplantation is enhancing. the amount of cd34+cells collected from cord blood compared to peripheral blood and bone marrow are less, but their collectionprocesure is easier. delay in freezing has negative effect on cells surveillance and reduce their ability in t...