A-56268 is a 6-O-methyl derivative of erythromycin A which has a spectrum of activity similar to that of erythromycin and is 1 log2 dilution more potent than erythromycin against most organisms that have been tested. The correlation of zone size diameters and MICs of A-56268 for 461 strains of bacteria isolated from clinical specimens was investigated. Based on anticipated levels in human serum...

In this paper, we consider a multihop wireless sensor network with multiple relay nodes for each hop where the amplify-and-forward scheme is employed. We present algorithmic strategies to jointly design linear receivers and the power allocation parameters via an alternating optimization approach subject to different power constraints which include global, local and individual ones. Two design c...

We extend the Goodness of Pronunciation (GOP) algorithm from the conventional GMM-HMM to DNN-HMM and further optimize the GOP measure toward L2 language learners’ accented speech. We evaluate the performance of the new proposed approach at phone-level mispronunciation detection and diagnosis on an L2 English learners’ corpus. Experimental results show that the Equal Error Rate (EER) is improved...

Coherent trellis-coded modulation (TCM) systems employing diversity combining are analyzed. Three different kinds of combining are considered: maximal ratio, equal gain, and selection combining (SC). First, the cutoff rate parameter is derived for equal gain combining (EGC) and SC assuming transmission over a fully interleaved channel with flat slow Rayleigh fading, which permits comparison wit...

When the concentration dependence of an enzymic reaction or a transport process can be described by the sum of two Michaelis-Menten terms, reliable data that relate reaction rate and substrate concentration can be obtained even when as much as 70 per cent of substrate was consumed during the assay. Each data pair consists of the average reaction rate during an assay and the concentration where ...