AIM To determine the prevalence and genotypic characterisation of extended spectrum beta-lactamases produced by gram negative bacilli isolated at Mbarara Regional Referral Hospital (MRRH). SAMPLES Gram negative clinical isolates. STUDY DESIGN Laboratory-based descriptive cross-sectional study. PLACE AND DURATION OF THE STUDY MRRH, June and August 2012. METHODS Gram negative clinical iso...

Antibiotic resistance is an increasing global problem resulting from the pressure of antibiotic usage, greater mobility of the population, and industrialization. Many antibiotic resistance genes are believed to have originated in microorganisms in the environment, and to have been transferred to other bacteria through mobile genetic elements. Among others, β-lactam antibiotics show clinical eff...

Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously char...

The most widely distributed blaCTX-M gene on a global scale is blaCTX-M-15. dissemination has been associated with clonal spread and different types of mobile genetic elements. objective this review was to describe the environments blaCTX-M-15 detected from Enterobacteriaceae in published literature Africa. A search for relevant articles performed through PubMed, AJOL, Google Scholar electronic...

conclusions it seems that besides the variety and prevalence of blatem and blactx, enormous mechanisms such as porin and leaking systems (efflux pumps) are responsible for the information of the a. baumannii resistance to disinfectants. the study on an accurate consideration of the resistance in strains and other microorganisms is advised. results in the current study, 131 a. baumannii isolates...

objective(s) extended-spectrum beta-lactamase (esbl) producing bacteria have an important role in nosocomial infections. due to the limited availability of information about the molecular epidemiology of esbl producing bacteria in mashhad, we decided to investigate about tem, ctx and shv esbls among urinary escherichia coli isolates in mashhad, a city in northeast iran. materials and methods   ...

Salmonella enterica is one of dangerous food-borne pathogens listed by the World Health Organization (WHO). In Vietnam, poultry most widely eaten meats and reported as a common source S. contamination. The aim this study was to examine multi-resistant strains, identify susceptibility antibiotics using 15 different types medications perform sequencing analyze antibiotic resistance genes, genotyp...

Escherichia coli (E. coli) is a zoonotic bacterial pathogen commonly found in human, birds and animals. The widespread use of broad-spectrum beta-lactams for poultry treatment, has resulted the production extended spectrum β-lactamases (ESBLs) E. coli. In this study, we analyzed antimicrobial resistance pattern isolates from broiler chickens ducks with clinical colibacillosis, investigated pres...

background and objective: organisms producing ctx-m β-lactamases are emerging as a source of resistance to oxyiminocefalosporins such as ceftriaxone and ceftazidime. however, the laboratory detection of these strains is not well defined. in this study, phenotypic assay for screening of extended-spectrum β-lactamases producing strains and molecular assay for the identification of ctx-m β-lactama...