INTRODUCTION The use of chemotherapy in node-negative, (O)Estrogen Receptor (ER)-positive breast cancer has changed significantly since the introduction of Oncotype DX to determine systemic recurrence risk based on tumour genomic signature. AIMS This study aims to METHODS A cohort study was undertaken, including consecutive patients with early node-negative, ER-positive breast cancer diagno...

 Diagnosis History. If classic symptoms of heartburn and acid regurgitation dominate a patient’s history, then they can help establish the diagnosis of GERD with sufficiently high specificity, although sensitivity remains low compared to 24-hour pH monitoring. The presence of atypical symptoms (Table 1), although common, cannot sufficiently support the clinical diagnosis of GERD [B*]. Testing....

10.4103/0970-2113.99248 A. K. Janmeja, Chandigarh; Abhishek Goyal, Chandigarh; Aditya Jindal, Chandigarh; Ajay Handa, Bangalore; Aloke G. Ghoshal, Kolkata; Ashish Bhalla, Chandigarh; Bharat Gopal, Delhi; D. Behera, Delhi; D. Dadhwal, Chandigarh; D. J. Christopher, Vellore; Deepak Talwar, Noida; Dhruva Chaudhry, Rohtak; Dipesh Maskey, Chandigarh; George D’Souza, Bangalore; Honey Sawhney, Chandig...

Lead (Pb) is well known for the containment of soil surfaces. In last few decades, phytoremediation has been most ideal technology to extract Pb from soil, involving numerous chemical reactions and cost analysis. The aim this study model optimize extraction contaminated via Pelargonium hortorum by comparing two modeling approaches: response surface methodology (RSM) artificial neural networks (...

We study the vortex lines that are a feature of many random or disordered three-dimensional systems. These show universal statistical properties on long length scales, and geometrical phase transitions analogous to percolation transitions but in distinct universality classes. The field theories for these problems have not previously been identified, so that while many numerical studies have bee...

OBJECTIVES Approximately one third of patients with non cardiac chest pain (NCCP) report a history of abuse, however no data exists on the prevalence of abuse among people with unexplained chest pain in the general population. We aimed to determine if there is a relationship between childhood sexual, physical, emotional abuse and unexplained chest pain, and to identify whether any potential rel...

Background National cancer control plans (NCCPs) are important documents that guide strategic priorities in cancer care and plan for the appropriate allocation of resources based on the social, geographic and economic needs of a population. Despite the emphasis on health equity by the World Health Organization (WHO), few NCCPs have ...

BACKGROUND Sweden has an extensive child and adolescent psychiatric (CAP) research tradition in which longitudinal methods are used to study juvenile delinquency. Up to the 1980s, results from descriptions and follow-ups of cohorts of CAP patients showed that children's behavioural disturbances or disorders and school problems, together with dysfunctional family situations, were the main reason...

The development of accurate quality performance measures in breast cancer surgery is extremely challenging as highlighted by Monica Morrow in a recent editorial 1 . Traditional quality measures in surgical oncology have focused on 30-day morbidity and mortality which are not relevant to breast cancer surgery which is typically associated with low morbidity and mortality. Dr Morrow suggests that...