Temporary paralysis is a rare manifestation of envenoming following the yellow Iranian scorpion, Odontobuthus doriae (O. doriae). Thus, to elucidate the underlying mechanism, we investigated the neurotoxic effect of venom in the sciatic nerve, the possible mechanism in a mice model. The neurotoxicity and temperature effects in the venom-induced neurotoxicity were examined using the mouse sciati...

Temporary paralysis is a rare manifestation of envenoming following the yellow Iranian scorpion, Odontobuthus doriae (O. doriae). Thus, to elucidate the underlying mechanism, we investigated the neurotoxic effect of venom in the sciatic nerve, the possible mechanism in a mice model. The neurotoxicity and temperature effects in the venom-induced neurotoxicity were examined using the mouse sciati...

objective (s): scar formation in injured peripheral nerve bed causes several consequences which impede the process of nerve regeneration. several animal models are used for scar induction in preclinical studies which target prevention and/or suppression of perineural scar. this study evaluates the translational capacity of four of physical injury models to induce scar formation around the sciat...

Objective(s):Diabetic neuropathy (DN) is a common complication of diabetes that leads to allodynia, impaired nerve conduction, and progressive sensory loss. The aim of this study was to observe the effect of a high-affinity cannabinoid receptors agonist, WIN 55,212-2, on thermal hyperalgesia, nerve conduction velocity and sciatic nerve histopathology in diabetic rats. Materials and Methods: Di...

temporary paralysis is a rare manifestation of envenoming following the yellow iranian scorpion, odontobuthus doriae (o. doriae). thus, to elucidate the underlying mechanism, we investigated the neurotoxic effect of venom in the sciatic nerve, the possible mechanism in a mice model. the neurotoxicity and temperature effects in the venom-induced neurotoxicity were examined using the mouse sciati...

Facial nerve neurofibromas are an uncommon entity, particularly in the intraparotid region. Three cases are presented herein, including the first reported case of both an intratemporal and intraparotid facial nerve malignant neurofibroma. To the best of our knowledge, this is the first medical publication to describe a neurofibroma involving both the intratemporal and intraparotid regions. The ...

The cell surface antigen distribution on traumatic neuroma Schwann cells and neurofibroma Schwann-like cells was characterized using monoclonal antibodies that define melanoma-associated antigens. Immunofluorescence staining of cultured cells, immunoprecipitation of radioiodinated antigens from cells placed in short-term cultures, and immunoperoxidase staining of frozen tissue sections revealed...

background and objective: sciatic nerve transection is characterized by a rapid wave of motoneuron death associated with progressive synaptic lesions. the purpose of this study was to evaluate the long term synaptic changes. materials and methods: this basic study was carried out on paraffin- or resin-embedded tissue blocks for evaluation of synaptophysin and choline acetyl transaferase (chat) ...

background peripheral nerve repair is often complicated by fibroblastic scar formation, nerve dysfunction, and traumatic neuroma formation. use of silicone may improve outcomes of these repairs. in this study, we tried to evaluate effectiveness of silicone gel on rats’ sciatic nerve repair, axon regeneration and scar formation around and in the nervous tissues. methods this experimental study w...