Occupational accidents severely deteriorate human capital, and hence negatively affect the productivity and competitiveness. But despite these negative points, there are still deficiencies in safety management performance and indicators. Therefore the safety issue needs an active management. For this reason, the writer has proposed an approach to evaluate organizations based on safety managemen...

BACKGROUND There is a lack of basic knowledge on the part of both clinicians and patients as to the indications for use and safety of herbs used during pregnancy and lactation. This is one article in a series that systematically reviews the evidence for herbs commonly used during pregnancy and lactation. OBJECTIVES To systematically review the literature for evidence on the use, safety and ph...

Most drugs are not tested for use during pregnancy, consequently, labeling, which may include information about fetal safety, includes nothing about dosing, efficacy, or maternal safety. Yet these are concerns of health care providers considering treatment of disease during pregnancy. Therefore, the practitioner treats the pregnant woman with the same dose recommended for use in adults (typical...

For female patients with rheumatoid arthritis, the availability of a host of new disease modifying antirheumatic drugs has raised important questions about fetal safety if a woman becomes pregnant while she is being treated. In addition, there is limited safety information regarding many of the older medications commonly used to treat rheumatoid arthritis in women of reproductive age. Current s...

Treatment for metastatic gastrointestinal stromal tumor (GIST) is a challenge, particularly in pregnant female because of the absence of safety data concerning imatinib use during pregnancy. We report a case of metastatic GIST surgically resected during pregnancy with a favorable outcome. A treatment strategy for GIST in pregnant patients should be carefully discussed by a multidisciplinary tea...