Individuals with or at risk for insulin-dependent diabetes (IDD) frequently have autoantibodies against an islet cell cytoplasmic (ICA) antigen thought to be a sialoglycolipid. However, we now report that preabsorption of ICA-positive sera with recombinant glutamate decarboxylase (human GAD 65 and/or GAD 67) reduced or blocked the ICA reactivity of 5/18 (27%) new-onset IDD patients and 7/18 (39...

Cytoplasmic islet cell antibodies are well-established predictive markers of IDDM. Although target molecules of ICA have been suggested to be gangliosides, human monoclonal ICA of the immunoglobulin G class (MICA 1-6) produced from a patient with newly diagnosed IDDM recognized glutamate decarboxylase as a target antigen. Here we analyzed the possible heterogeneity of target antigens of ICA by ...

In this paper, a hybrid meta-heuristic algorithm, based on imperialistic competition algorithm (ICA), harmony search (HS), and simulated annealing (SA) is presented. The body of the proposed hybrid algorithm is based on ICA. The proposed hybrid algorithm inherits the advantages of the process of harmony creation in HS algorithm to improve the exploitation phase of the ICA algorithm. In addition...

ICA decomposes a set of features into a basis whose components are statistically independent. It minimizes the statistical dependence between basis functions and searches for a linear transformation to express a set of features as a linear combination of statistically independent basis functions. Though ICA has found its application in face recognition, mostly spatial ICA was employed. Recently...

Abstract The detection of sensor faults has proven to be easier through data-driven methods which rely on historical data collected from sensors that are placed at various locations in a process plant. Since the distribution industrial variables is random and non-Gaussian, independent component analysis (ICA) method been better suited for fault (FD) problems. Whenever comes with any level noise...

Spatial smoothing is a widely used preprocessing step in functional magnetic resonance imaging (fMRI) data analysis. In this work, we report on the spatial smoothing effect on task-evoked fMRI brain functional mapping and functional connectivity. Initially, we decomposed the task fMRI data into a collection of components or networks by independent component analysis (ICA). The designed task par...

In this research, an integrated approach is presented to simultaneously solve quay crane scheduling and yard truck scheduling problems. A mathematical model was proposed considering the main real-world assumptions such as quay crane non-crossing, precedence constraints and variable berthing times for vessels with the aim of minimizing vessels completion time. Based on the numerical results, thi...