question of the aetiology of gastric ulcer is fully discussed. The authors consider that acute primary ulcer often commences as a hemorrhage, and that chronic ulcer, although it may be a sequel of an acute ulcer, is probably frequently due to impaired nutrition of the mucous membrane of the stomach consequent upon arterial degeneration. It has always seemed to us that a hemorrhage is the most l...

An idiopathic peptic ulcer is defined as an ulcer with unknown cause or an ulcer that appears to arise spontaneously. The first step in treatment is to exclude common possible causes, including Helicobacter pylori infection, infection with other pathogens, ulcerogenic drugs, and uncommon diseases with upper gastrointestinal manifestations. When all known causes are excluded, a diagnosis of idio...

Buruli Ulcer is a devastating skin disease caused by the pathogen Mycobacterium ulcerans. Emergence and distribution of Buruli ulcer cases is clearly linked to aquatic ecosystems, but the specific route of transmission of M. ulcerans to humans remains unclear. Relying on the most detailed field data in space and time on M. ulcerans and Buruli ulcer available today, we assess the relative contri...

Only a few papers have been published about unusual localisations of pressure ulcer. To date, no papers were published presenting pressure ulcer on external genitals in women. The paper presents the mechanism of origin of vulval pressure ulcer, surgical treatment (excision of lesion tissue of the pressure ulcer) and reconstruction of the vulva. The patient, aged 50, has been paraplegic for 20 y...

Introduction The purpose of this white paper is to review the currently available scientific evidence related to nutrition and hydration for pressure ulcer prevention and treatment in adults; introduce the nutrition recommendations from the new National Pressure Ulcer Advisory Panel (NPUAP)-European Pressure Ulcer Advisory Panel (EPUAP) Guidelines for Pressure Ulcer Treatment; and review resear...

Ulcer is a common problem associated with NSAID’s use. The use of plants to treat and cure diseases is common practice since ancient times because of people blind faith on safety of plant’s use. The present study aimed to evaluate anti-ulcer activity of Dalbergia sissoo in alcohol and aspirin induced ulcerative rat models. Animals were divided into four groups. Group I was disease control, grou...

BACKGROUND Ulcer type and non-ulcer type interstitial cystitis/bladder pain syndromes (IC/BPS) are considered different disease entities. Thus, intravesical botulinum toxin A (BoNT-A) treatment outcomes could differ for each entity. OBJECTIVES To evaluate and compare the treatment outcomes of BoNT-A injections for treatment of each IC/BPS type. STUDY DESIGN Prospective interventional study....