Breast cancer is a major public health problem worldwide. Important advances have improved survival, but early detection remains the main clinical challenge in reducing mortality. Currently, mammography is the ‘gold standard’ tool for breast cancer screening. However, the search for an early breast cancer detection method is the subject of extensive research. Although infrared imaging or breast...

breast cancer is one of the most common malignancies in the world. the most important prognostic factor in this cancer is the stage of the tumor. detection of lymph nodes with or without malignancy is essential for determining the stage of the tumor and setting a therapeutic plan. there are different methods for isolating lymph nodes in surgical specimens of breast cancer in the pathology depar...

Background: Recently, it has been indicated that X-ray coherent scatter from biological tissues can be used to access signature of tissue. Some scientists are interested in studying this effect to get early detection of breast cancer. Since experimental methods for optimization are time consuming and expensive, some scientists suggest using simulation. Monte Carlo (MC) codes are the best...

background: breast cancer is one of the most important diseases in females. malaysian women have not excluded. according to the malaysian oncology society [1], about 4% of women (who are 40 years old and above) have involved by breast cancer. masses and microcalcifications are two important signs for breast cancer diagnosis on mammography. according to our estimation, radiologists could diagnos...

background: exposure to endogenous hormones such as estrogen is known as a lifetime breast cancer (bc) risk factor. polymorphisms in genes that are involved in the steroidogenic process, such as cytochrome p450c17alpha ( cyp17) , affect individuals’ susceptibility to bc. in iran, the highest incident of bc is among young women. this study aimed to find prevalence of single nucleotide polymorphi...

background: the breast cancer is the most prevalent cancer among women, on the other hand absence of myoepithelial cells play a pivotal role in pathogenesis of this cancer. thus we aimed to investigate the possible abilities of the molecular assay technique to find a relationship between mammary serine protease inhibitor (maspin) gene expression possibly secreted by myoepithelial cells, grade o...

introduction: lymphoscintigraphy is imaging of the lymphatic system and has been integrated into the sentinel node mapping procedures. lymphoscintigraphy usually encompasses early or delayed static images. however, immediate dynamic imaging of the lymphatic basins and tumors has also been used as an adjunct lymphoscintigraphy imaging. the aim of this study was to assess the role of early dynami...

the focus of this study was to determine if early detection of mutant p53 accumulation may be an early indicator of tumor aggressiveness and transformation to invasive breast cancer. for this purpose, the p53 content of 100 human breast biopsies classified as ductal carcinoma (dcis), was evaluated by immunohistochemical method. all specimens were microscopically classified into histologic types...