The extracellular calcium-sensing receptor (CaR) on the parathyroid cell surface negatively regulates secretion of parathyroid hormone (PTH). CaR has an important rule in diseases. Cinacalcet hydrochloride, an allosteric agonist of this receptor was approved by FDA in 2004 for treatment of secondary hyperparathyroidism. Cinacalcet is indicated for the treatment of hypercalcemia in patients with...

Parafascicular (Pf) neurons receive cholinergic input from the pedunculopontine nucleus (PPN), which is active during waking and REM sleep. There is a developmental decrease in REM sleep in humans between birth and puberty and 10-30 days in rat. Previous studies have established an increase in muscarinic and 5-HT1 serotonergic receptor-mediated inhibition and a transition from excitatory to inh...

The paper presents models of car dynamics with varying complexity. Joint coordinates and homogenous transformations are used to model the motion of a car. Having formulated the models of the car, we discuss the influence of the complexity of the model on numerical efficiency of integrating the equations describing car dynamics. Methods with both constant and adaptive step size have been applied...

The control of car following is essential due to its safety and its operational efficiency. For this purpose, this paper builds a model of car following behavior based on ARMAX structure from a real traffic dataset and design a Model Predictive Control (MPC) system. Based on the relative distance and relative acceleration of each instant, the MPC predicts the future behavior of the leader vehic...

Car painters are exposed to organic solvents during their work. Several sets of official regulations have therefore been adopted in Norway in recent years to reduce the exposure. This study evaluated some of the effects of these regulations, by measuring the levels of exposure to organic solvents in six car-painting garages and relating them to the limit values in Norway. Both stationary and pe...

With the increase of unstructured social media data, sentiment analysis can be applied to infer useful information to assist organizations and their customers. We propose a model for feature-based sentiment analysis using ontology to address queries like:“which car is more comfortable?, which car has better performance and interior?”. Feature based sentiment analysis is done using SentiWordNet ...

A transient heat transfer mathematical model for the prediction of temperature distribution in the car body during primer baking has been developed by considering the thermal radiation and convection in the furnace chamber and transient heat conduction governing equations in the car framework. The car cockpit is considered like a structure with six flat plates, four vertical plates representing...

An efficient vision system is proposed for multiple car tracking on the highway. The main modules of the system are: lane detection, separate 2D model-based trackers (rectangular model for passing car and U-shape model for distant car), heuristic car detection, and a process coordinator. In the system, the dynamical creation and termination of tracking processes optimizes the amount of spent co...