Adulteration of allegedly "natural herbal medicines" with undeclared synthetic drugs is a common and dangerous phenomenon of alternative medicine. The purpose of the study was to develop a procedure for detection of most common synthetic adulterants in herbal remedies, using high-pressure liquid chromatography-electrospray tandem mass spectrometry (LC-ESI-MS-MS). Eighty drugs belonging to vario...

Rhein (4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid, cassic acid) is a pharmacological active component found in Rheum palmatum L. the major herb of San-Huang-Xie-Xin-Tang (SHXXT), a medicinal herbal product used as a remedy for constipation. Here we have determined multiple bioactive components in SHXXT and investigated the comparative pharmacokinetics of rhein in rats. A sensitive and...

Herbal medicines in treatment of cancer as complementary and alternative therapy are accepted increasingly with growing scientific evidences of biomedical research and clinical trials. Anticancer drugs discovered from herbal medicines have a long history and some of them have been used in clinical setting as the conventional anticancer drugs. Actually, herbal medicines are a source for anticanc...

Liver disorder may cause liver inflammation or tissue injury and affects liver physiologic condition. Natural products that are found in the form of vegetables, fruits, plant extract, herbs, and animals, have been traditionally and clinically used for treating liver disorders. They are specific chemical compounds that usually have biological activities for use in drug evaluation and design. Man...

Kampo herbal remedies are reported to have a wide range of indications and have attracted attention due to reports suggesting that these remedies are effective when used in disease treatment while maintaining a favourable quality of life. Yokukansan, also known as TJ-54, is composed of seven herbs; Angelica acutiloba, Atractylodes lancea, Bupleurum falcatum, Poria cocos, Glycyrrhiza uralensis, ...

Snake bite is a major health hazard that leads to high mortality and great suffering in victims. The remedies are of great interest since they may have recognizable therapeutic or toxic effects and are steeped in cultural beliefs that invariably conflict with formal health care practices. The study of the interaction between plants and people is invaluable in discovering new herbal medicines an...

Standardization of herbal drugs is the need of the hour as the use and practice of traditional herbal drugs has increased tremendously. The main objective of the present study is to standardize the root tubers of Aconitum heterophyllum as per pharmacopoeial testing protocol which include powder microscopy, physico-chemical screening, HPTLC fingerprinting and GC-MS analysis. Preliminary phytoche...

Background and objectives: Herbal aromatic waters are one of the products used in the Iranian traditional medicine. These products have small amount of essential oil. The purpose of this study was to identify the effective substances of herbal aromatic waters by various techniques (GC/FID and GC/MS). It is hoped that with assessment of these compounds by mentioned techniques a ...