Background & Objective: Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer that may be caused by Human papillomavirus (HPV), especially in immunosuppressed patients. However, the role of the mucosal types of HPV in SCC patients with normal immunity has not been extensively confirmed. The aim of this study was to investigate the association...

OBJECTIVE Approximately 90% of squamous carcinomas of the cervix harbor the human papillomavirus and type 16 has been detected in nearly 50% of cases. Recent studies in mice have shown that the human papillomavirus type 16 E7 oncoprotein contains peptide epitopes that are processed and presented in association with a major histocompatibility antigen for recognition by cytolytic T lymphocytes. W...

Human papillomavirus (HPV) infection is the leading cause of cervical cancer world-wide. Here, we show that native HPV particles produced in a differentiated epithelium have developed different strategies to infect the host. Using biochemical inhibition assays and glycosaminoglycan (GAG)-negative cells, we show that of the four most common cancer-causing HPV types, HPV18, HPV31, and HPV45 are l...

Despite the increasing evidence of human papillomavirus (HPV) vertical transmission, this route is regarded as less clinically important because of the detections of transient HPV DNA. However, recent studies have provided clear evidence of papillomavirus productive infection in lymphocytes, placenta, and bovine fetal tissue. Furthermore, a model of papillomavirus latency has been recently prop...

Despite the increasing evidence of human papillomavirus (HPV) vertical transmission, this route is regarded as less clinically important because of the detections of transient HPV DNA. However, recent studies have provided clear evidence of papillomavirus productive infection in lymphocytes, placenta, and bovine fetal tissue. Furthermore, a model of papillomavirus latency has been recently prop...

REVIEWS EDITIONS SUBSCRIPTION EDITORIAL POLICY CONTACTS N 1–2 (179–180) 2022. P. 93–96 EXPERIENCE OF PRIMARY HPV TESTING IN CERVICAL CANCER SCREENING O. V. Bondar, A. I. Rybin, Muzyka Odesa National Medical University , Odesa, Ukraine The main cause of cervical cancer in almost 100% cases is the human papillomavirus (HPV), which also involved development other cancers lower genital tract. malig...

DNA of human papillomavirus (HPV) type 45, a new HPV type 18-related papillomavirus of the genital tract, was cloned from a recurrent cervical lesion displaying mild to moderate dysplasia with koilocytosis. HPV-45 DNA was identified in paraffin sections of biopsies of both the initial and recurrent lesions of the patient, taken 7 months apart. HPV-45 DNA hybridized efficiently to that of many d...

Background: The pathogenesis of endometriosis is still debatable, and many studies reported a predisposition to infectious immunological factors. In this study, we aimed evaluate the human papillomavirus (HPV) positivity in pain-related symptoms infertility. Methods: cross-sectional 410 patients were enrolled study. HPV-positive (n = 202) HPV-negative 208) compared with symptoms, infertility, e...