نتایج جستجو برای: in vitro release studies

تعداد نتایج: 17166397  

Abu Shara Shamsur Rouf Abul Kalam Lutful Kabir, Harun-Or- Rashid Md. Zakir Hossaina

     The purpose of this work was to develop once daily sustained release (SR) matrix tablets of naproxen, an anti-inflammatory agent. The tablets were prepared by wet granulation method along with hydrophilic matrix materials like Methocel K 15M CR and Methocel K 100M CR. The granules were evaluated for bulk density, angle of repose, compressibility index, total porosity and drug content. The ...

حسن زاده, فرشید, رستمی, محبوبه, صادقی, حسین, نیکبخت کشکولی, حافظ, ورشوساز, ژاله,

Background and purpose: Boron Neutron Capture Therapy (BNCT) is a promising radiotherapy based on the accumulation of Boron into the tumor and subsequent irradiation with low energy neutrons. It leads to the decay of 10B to 7Li and α particle, causing the death of the neoplastic cells.  Here we report some chitosan modified nanoparticles bearing boron phenyl alanine (BPA) as an inexp...

Journal: :iranian journal of pharmaceutical research 0
xiaoyun zhang school of pharmacy, lanzhou university, lanzhou, 730000, china, r.o.c. hua qiao drug clinical trial institution, the first hospital of lanzhou university ying chen school of pharmacy, lanzhou university lin li school of pharmacy, lanzhou university huxiong xia department of pharmaceutics, the first hospital of lanzhou university yanbin shi school of pharmacy, lanzhou university

low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (lmwh-isl-sln) was developed for injective application. the morphological observation, particle diameter and zeta potential of lmwh-isl-sln were characterized using transmission electron microscopy (tem) and a malvern zetasizer. its entrapment efficiency (ee) and drug loading (dl) were determined by ultracen...

Journal: :iranian journal of pharmaceutical research 0
meysam mohseni department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran kambiz gilani department of pharmaceutics, school of pharmacy, tehran university of medical sciences, tehran, iran zohreh bahrami school of chemistry, college of science, university of tehran, tehran, iran noushin bolourchian department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran seyed alireza mortazavi department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran

the goal of this research is preparation, optimization and in-vitro evaluation of rifampin-loaded silica nanaoparticles in order to use in pulmonary drug delivery. nanoparticles are exhaled because of thier small size, preparation of nanoaggregates in micron-sized scale and re-disrpersion of them after the deposition in the lung is one approach in order to overcome this problem, which we used i...

Myrna D Paul C Thakur M, Thompson D VKD

Background: Vajikarana herbs from Ayurveda are known to enhance the sexual performance in folklore. The objective is to evaluate their effect by molecular and pharmacological screening. Materials and Methods: In the present study, the effect of four Vajikaran Rasayana herbs on penile erection, sperm count, seminal fructose content in vivo and nitric oxide (NO) release in vitro was assessed. Pen...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز 0

a semi-empirical mathematical model for predicting physical part of ignition delay period in the combustion of direct - injection diesel engines with swirl is developed . this model based on a single droplet evaporation model . the governing equations , namely , equations of droplet motion , heat and mass transfer were solved simultaneously using a rung-kutta step by step unmerical method . the...

Journal: :iranian journal of pharmaceutical sciences 0
majid saeedi department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences jafar akbari department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iran. katayoun morteza-semnani department of medicinal chemistry, faculty of pharmacy, mazandaran university of medical sciences, sari, iran ali azarashk department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iran.

drug delivery via buccal mucosa by means of buccoadhesive formulations offer distinct advantages over peroral administration. recently, plant gums and exudates have been screened for their use as pharmaceutical adjuvants. the aim of this study is to evaluate matrix tablets containing plantago psyllium seed mucilage in addition to carbopol as a mucoadhesive agent, and propranolol hydrochloride a...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان 1388

abstract recent studies suggest that prelistening activities play an important role in the development of listening comprehension (e.g. long 1990;chiang and dunkel 1992; schmidt-rinehart 1994; jensen and hansen 1995; robinson et al., 1995; buck, 1995; foster and skehan,1996; teng 1996; robinson, 2001; chang and read 2006). in line with previous studies and to shed light on a new aspect of sche...

Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

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