نتایج جستجو برای: mmp
تعداد نتایج: 17848 فیلتر نتایج به سال:
Matrix metalloproteinase (MMP)-2 and MMP-9 are gelatinases that take part in several reproductive processes. The aim of this study was to measure levels MMP-2 fractionated stallion ejaculates, evaluate the association between these components semen quality, sperm longevity during cooled storage. Semen quality were assessed separately for sperm-rich fractions (HIGH), sperm-poor (LOW), whole ejac...
Sedum middendorffianum Maxim (SMM) is a Korean endemic plant belonging to the Crassulaceae family. This study aimed investigate antitumor effects of SMM extract on human ovarian cancer cells. Among five plants grown in Korea, showed most potent cytotoxicity cells and had little effect normal surface epithelial Furthermore, we revealed that dose-dependently induced apoptosis A2780 SKOV3 The mark...
Purpose: In retinal endothelial cells, homocysteine (Hcy) activates matrix metalloproteinase (MMP)-9, which results in apoptosis. This study investigated these effects of Hcy human trabecular meshwork cells (HTMC).Methods: HTMC cultures using 5 mM low or 20 high glucose (HG)-containing media were exposed to 100 μM for 3 days. Cell viability was assessed with the MTT (3-[4, 5-dimethylthiazol-2-y...
breast cancer patients are susceptible to infections such as candidiasis. due to the importance and the role of matrix metalloproteinases (mmp) in breast cancer progression and its correlation with tumor metastasis, we analyzed the serum level of mmps -2, -3, -9 and tissue inhibitor of matrix metalloproteinase-1 (timp-1) in breast cancer bearing mice in the presence of systemic candida ...
background: previous studies have shown that some cytokines have protective effects on cartilage in joint diseases. in the current study, effects of il-4 against morphological changes and tissue degradation induced by il-1α on bovine nasal cartilage (bnc) explants were investigated. methods: fresh bnc samples were prepared from a slaughterhouse under sterile conditions. bnc explants culture was...
background: leukemia is a malignant proliferative disorder of the hematopoietic cells. the important role of angiogenesis in leukemia has been reported by several studies. matrix metalloproteinases (mmps) are a large group of endopeptidases which degredate the extracellular matrix and play an important role in angiogenesis. objective: the present study was conducted to evaluate the patterns of ...
مقدمه: فعالیت ورزشی منظم یک شیوه غیردارویی موثر در پیشگیری از مرگ و میر ناشی از بیماری های قلبی عروقی در بیماران دیابتی است. لذا هدف از تحقیق حاضر، بررسی اثر 8 هفته تمرین شنا بر سطوح قلبی ماتریکس متالوپروتئنیاز-2 (mmp-2) و فاکتور رشد تبدیل- بتا یک (tgf- β1) در رت های دیابتی بود. روش ها: 28 سر موش صحرایی نر ویستار به صورت تصادفی به 4 گروه (7 تایی) کنترل، دیابت، تمرین، دیابت- تمرین تقسیم شدند. دی...
ObjectiveThe aim of this study was to observe the spatial distribution and dynamic changes matrix metalloproteinase (MMP)-2, MMP-9, collagen in stent restenosis (ISR) explore their influence on ISR.MethodsSixty Z type stents were implanted into common iliac arteries minipigs, which divided 10 groups (six each group) according euthanasia time (6 hours, 1, 3, 7, 14, 28, 56, 84, 168, 336 days). Af...
Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...
Background and purpose: The expression of growth factors, proteolytic enzymes, fibrogenic factors, and cytokines are altered in Helicobacter pylori (H. pylori) infected gastric mucosa. Matrix metalloproteinases (MMP) are a family of zinc-dependent homologous enzymes digesting most of the components of the extracellular matrix and basement membrane and are involved in remodeling and functioning o...
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