Objective- To studylocal effect of prostaglandin E1on sciatic nerve regeneration Design- Experimental study Animals- Sixty male healthy white Wistar rats Procedures- Sixty animals were divided into four experimental groups (n = 15), randomly: Trasnsected (TC), Sham-operation (SHAM), control (CHIT) and prostagl...

introduction: transplantation of bone marrow stromal cells (bmscs) or schwann cells (scs) can increase axonal regeneration in peripheral nerve injuries. based on our previous investigations, the goal of the present work was to examine the individual and synergistic effects of the two different cell types in sciatic nerve injury . we pursued to evaluate the effects of bmscs and scs co-transplant...

To evaluate the effects of local administration of the fetal brain extract (FBE) on the crushed peripheral nerve, 15 male Wistar rats were used. The right sciatic nerve of 10 rats was locally underwent the tense compression for 30 seconds and then randomly divided into experimental and control (sham) groups. The remained rats were considered as intact animals. Treatment was commenced weekly, by...

background: bone marrow and umbilical cord stromal cells are multipotential stem cells that have the ability to produce growth factors that play an important role in survival and generation of axons. the goal of this study was to evaluate the effects of the two different mesenchymal stem cells on peripheral nerve regeneration. materials and methods: in this experimental study, a 10 mm segment o...

background: initial studies have shown that low-energy ultrasound stimulates living tissue cells to reduce regeneration or speed up their recovery. the purpose of this study was to examine the effects of various ultrasound parameters on the speed of recovery in injured sciatic nerves. methods: nmri mice (n = 200) with injured left paw, caused by crushing their sciatic nerves, were randomly sele...

conclusions our anesthesia method was sciatic and femoral nerve block under double ultrasonic and nerve stimulator guidance. case presentation in this case report, we present a patient who had tibia and fibula fractures and a symptomatic severe critical aortic stenosis which was diagnosed during a preoperative visit. the patient had exertional dyspnea, palpitations and fainting history, but he ...

excessive scarring; paralleling the process in tendon reconstruction of the hand. inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. methods:  thirty female rats (~200 g) were randomly distributed into two groups (n=15...

tumors that originate from the nerve sheath comprise diverse groups -perineuroma, neurofibroma and schwannoma. the epithelioid variant of these tumors is uncommon and mostly seen in malignant counterparts. although this type of morphology is well recognized in peripheral nerve sheath tumors, its presence in the central nerves is rarely reported. very few cases of nerve sheath tumors have been r...

Objective(s): Peripheral nerves are commonly damaged. Although the nerve autograft still subsists the gold standard in surgery of nerve injury gaps, it has severe detriment. The egg shell membrane (ESM) is a natural material, which has a great potential in practice. The aim of this survey was to appraise the effect of lycopene and the ESM nerve guidance channel on scia...