نتایج جستجو برای: oxidant stress

تعداد نتایج: 448526  

Journal: :The American Journal of Clinical Nutrition 1998

2012
A. McCarthy J. McKinley T. Lynch

What is it about the dopaminergic neurones of the substantia nigra pars compacta (SNpc) and the cholinergic neurones of the dorsal motor nucleus of the vagus (DMV) that makes them particularly prone to the neurodegenerative changes found in Parkinson’s disease? If mitochondrial oxidant stress is accepted as an important step in the pathogenesis or Parkinson’s disease, are these cell groups inhe...

Objective(s): The present study sought to evaluate the beneficial effects of histidine (His) on oxidative stress, tumor necrosis factor alpha (TNF-α), renal histological alterations and anti-oxidant enzymes gene expressions in type 2 diabetic rats.Materials and Methods: Streptozotocin/nicotinamide (STZ/NA) induced diabetic rats were used...

Journal: :The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2012
Sebahat Başyığıt Halide Akbaş İnci Süleymanlar Didem Kemaloğlu Serkan Koç Gültekin Süleymanlar

BACKGROUND/AIMS Helicobacter pylori infection has been suggested to be associated with atherosclerosis. The issue is still controversial. It is well known that abnormal lipid profile and oxidative stress are related to atherosclerosis and the measurement of carotid intima-media thickness. The aim of this study was to investigate carotid intima-media thickness and oxidative stress along with lip...

2017
Ashley C. Kramer Jenna Weber Ying Zhang Jakub Tolar Ying Y. Gibbens Margaret Shevik Troy C. Lund

Metabolism of oxidative stress is necessary for cellular survival. We have previously utilized the zebrafish as a model of the oxidative stress response. In this study, we found that gata1-expressing erythroid cells contributed to a significant proportion of total-body oxidative stress when animals were exposed to a strong pro-oxidant. RNA-seq of zebrafish under oxidative stress revealed the in...

2002
JYH CHANG JEAN YUE LIU LOU ANN BROWN ROBERT E. MARC ELIZABETH KLINGS MARTIN JOYCE-BRADY

Jean, Jyh Chang, Yue Liu, Lou Ann Brown, Robert E. Marc, Elizabeth Klings, and Martin Joyce-Brady. -Glutamyl transferase deficiency results in lung oxidant stress in normoxia. Am J Physiol Lung Cell Mol Physiol 283: L766–L776, 2002. First published May 3, 2002; 10.1152/ ajplung.00250.2000.— -Glutamyl transferase (GGT) is critical to glutathione homeostasis by providing substrates for glutathion...

Journal: :Clinical and experimental pharmacology & physiology 2006
Shyam S Sharma Sufyan G Sayyed

1. Diabetic neuropathy is one of the most common complications of diabetes and oxidative stress has been implicated to play a major role in its pathophysiology. 2. In the present study, we targeted oxidative stress using trolox, an anti-oxidant, in streptozotocin-induced diabetic neuropathy in rats. 3. Compared with control rats, diabetic rats showed significant deficits in motor nerve conducti...

Journal: :The Turkish journal of pediatrics 2015
Ersin Sayar Sebahat Özdem Gülbahar Uzun Ali İşlek Aygen Yılmaz Reha Artan

In our study, we aimed to investigate ischemia modified albumin (IMA) as an oxidative stress marker, as well as other oxidant and antioxidant markers that have not been evaluated in children with celiac disease. A total of 37 pediatric patients who were diagnosed with celiac disease (CD) and 29 healthy children were enrolled in this prospective study. We evaluated the IMA, total oxidant status,...

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