Introduction: The aim of present study was to investigate the effects of royal jelly (RJ) on the number of Nissl-stained neurons in caudate putamen unit (CPU) and substantia nigra pars compacta (SNC) and the thickness of gray (TGm) and white matter (TWm) of cerebral and cerebellar cortex in male rats with Parkinson’s disease (PD). Methods: Seventy five Sprague-Dawley adults’ male ra...

The key to successful long-term peritoneal dialysis (PD) is permanent and safe access to peritoneal cavity. The two most commonly used Tenckoff catheters for PD are the straight and coiled catheters. The present study was undertaken to assess the catheter survival, catheter associated infections, and all cause mortality and to compare the straight with coiled catheters in PD. During April 1997-...

parkinson’s disease (pd) is a prevalent neurodegenerative disease that usually affects individuals over 50 years of age. age at onset in a small subset of pd cases is considerably lower, and these are considered early-onset pd (eopd) patients. most pd cases appear sporadic, but approximately 15% are familial, and some of the familial cases exhibit mendelian inheritance. genetic analysis of fami...

background: cognitive impairment in patients with parkinson’s disease (pd) mainly involves executive function (ef). the frontal assessment battery (fab) is an efficient tool for the assessment of efs. the aims of this study were to determine the validity and reliability of the psychometric properties of the persian version of fab and assess its correlation with formal measures of efs to provide...

Objective: Previous studies showed that grape seed extract (GSE) is an excellent natural substance with potent antioxidant effect and free radical scavenger. This study aimed to evaluate the effect of GSE on motor dysfunctions and thalamic local Electroencephalography (EEG) frequency bands' powers in rats with Parkinson's disease (PD). Materials and Methods: In this study 8 µg 6-hydroxydopamin...

Background and Objective: Parkinson's disease (PD) is a movement disorder with debilitating symptoms. Available treatments for PD mainly include its symptomatic relief with no prevention of its progression. Due to the iron-chelating and antioxidant effect of phytic acid (PA), this study was conducted to assess its protective effect in 6-hydroxydopamine-induced model of PD in rat. Materials and ...

Depression is common and may occur at any stage in the long history of Parkinson’s disease, markedly affecting a patient’s threshold to discomfort, but it is particularly difficult to assess before clear clinical features are evident. The rate of depression in patients with Parkinson’s disease vary, partly because of differences in the definition of depression, difficulties in distinguishing be...