نتایج جستجو برای: protein domain analysis

تعداد نتایج: 4069012  

براتی , بابک, ابراهیمی, فیروز , حاجی زاده , عباس , رضائیانی, سیامک , هنری , حسین ,

   Backgrounds & Aims: Botulism is caused by botulinum toxin. The best way to avoid the neurotoxin syndrome caused by BONT/B is to use recombinant vaccine made of BONT/B binding domain because binding domain has sufficient epitops to stimulate immune response. Materials & Methods: Initially BONT/B binding domain gene sequence were obtained from GenBank. Then the primers were designed. PCR react...

Kianifard D Mousavi Z, Rezaee F

Background: Male infertility has many causes, including genetic infertility. The NOP2/Sun domain family, member7 (Nsun7) gene, which encodes putative methyltransferase Nsun7, has a role in sperm motility. The aim of the present study was to investigate the effect of the T26248G polymorphism on Nsun7 protein function and its role in male infertility. Materials and Methods: Semen samples were col...

Journal: :Acta Crystallographica Section F Structural Biology Communications 2019

Background and Objectives: Botulism syndrome is caused by one of the seven botulinum neurotoxins. The toxins binding domain have immunogenicity effect and can be used as a recombinant vaccine candidate against botulism disease. Due to the low immunogenicity of recombinant protein , the use of an appropriate vehicle for antigen delivery to target cells is inevitable. The purpose of this study ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی اصفهان - دانشکده منابع طبیعی 1391

چکیده ارتباط بین عوامل محیطی با گونه های گیاهی همیشه یک موضوع اصلی در اکولوژی گیاهی بوده است. تعیین این روابط کمی هسته اصلی مدلسازی پیش بینی پراکنش مکانی بالقوه گونه های گیاهی به شمار می رود. این مدل ها به منظور کسب اطلاعات درباره پراکنش مکانی گونه ها، شناسایی زیستگاههای مناسب و ارزیابی آثار تغییر اقلیم در پراکنش مکانی گونه ها به کار گرفته می شوند. از اهداف این مطالعه، شناسایی عوامل محیطی موثر...

Hosseinzadeh Colagar A Khosronezhad N, Mortazavi SM

Background: Male infertility has many causes, including genetic infertility. The NOP2/Sun domain family, member7 (Nsun7) gene, which encodes putative methyltransferase Nsun7, has a role in sperm motility. The aim of the present study was to investigate the effect of the T26248G polymorphism on Nsun7 protein function and its role in male infertility. Materials and Methods: Semen samples were col...

Journal: :iranian biomedical journal 0
مهریار حبیبی رودکنار mehryar habibi roudkenari سعید بوذری saeid bouzari مانا علومی mana oloomi انیس جعفری anis jafari نادر شاهرخی nader shahrokhi محمدعلی شکرگزار mohammad ali shokrgozar

fusion of two genes at dna level produces a single protein, known as a chimeric protein. immunotoxins are chimeric proteins composed of specific cell targeting and cell killing moieties. bacterial or plant toxins are commonly used as the killing moieties of the chimeric immunotoxins. in this investigation, the catalytic domain of shiga-like toxin (a1) was fused to human granulocyte macrophage c...

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