OBJECTIVE Implementation of evidence-based care for serious mental illnesses such as bipolar disorder has been suboptimal. Improving and sustaining concordance with clinical practice guidelines has been a cornerstone of efforts to enhance evidence-based care and improve outcomes. For bipolar disorder, however, there has been only one regional controlled trial reporting guideline concordance, an...

BACKGROUND There is an increased interest of individuals in quantifying their own health and functional status. The aim of this study was to examine the concordance of answers to a self-administered questionnaire exploring health and functional status with information collected during a full clinical examination performed by a physician among cognitively healthy adults (CHI) and older patients ...

BACKGROUND Since individual-level income is difficult to collect, investigators often rely on group-based measures derived from census data. No study has assessed the use of residential property values as an indicator of individual material circumstances. We aimed to compare two proxy indicators of material circumstances, one based on residential value and the other on median census tract incom...

Relative self-linking and linking \numbers" for pairs of oriented knots and 2{component links in oriented 3{manifolds are de ned in terms of intersection invariants of immersed surfaces in 4{manifolds. The resulting concordance invariants generalize the usual homological notion of linking by taking into account the fundamental group of the ambient manifold and often map onto in nitely generated...

BACKGROUND Early puberty onset has been related to future chronic disease; however breast bud assessment in large scale population studies is difficult because it requires trained personnel. Thus our aim is to assess the validity of self and maternal breast bud detection, considering girl's body mass index (BMI) and maternal education. METHODS In 2010, 481 girls (mean age = 7.8) from the Grow...