Introduction: Sexhormones are one of most important factors in difference of learning and memory between tow sexes (male & female). High concentration of estrogen and androgen receptors and mechanism of testosterone and estrogen production in learning and memory center, especially in hippocampus show the role of this receptors, sexhormons and P450 enzymes in spatial memory. Consequently, in thi...

Background: Testosterone and its metabolites have important roles in learning and memory. The current study has conducted to assess the effect of pre-training, post-training and pre-probe trial intrahippocampal CA1 administration of 3 alpha-anderostanediol (one of the metabolites of testosterone) and indomethacin (as 3 alpha-hydroxysteroid dehydrogenase enzyme blocker) on acquisition, consolida...

 Introduction: Patients with epilepsy can have impaired cognitive abilities. Many factors contribute to this impairment, including the adverse effects of antiepileptic drugs like Gabapentin (GBP). Apart from anti-epilectic action, Gabapentin is used to relieve ethanol withdrawal syndrome. Because both GBP and ethanol act on GABA ergic system, the purpose of this study was to evaluate their effe...

some animal models have been used to study alzheimer's disease (ad). ad is an irreversible progressive neurodegenerative disease and the most common cause of dementia. animal studies have shown that there is a relation between decrease in cholinergic functions in the nucleus basalis of meynert (nbm) and loss of learning capability and memory. the aim of this study was to investigate the ef...

objective(s) the objective of this study was to determine the effect of aqueous extract of origanum vulgare l. ssp. viridis (org) on discrimination learning and long term potentiation (ltp) in ca1 region of the rat hippocampus. materials and methods a group of adult male wistar rats weighing 275±25 g received aqueous extract of org (150, 300, 450 mg/kg/day) by intraperitoneal injection for one ...

objectives: the visual-motor skill is one of the major factors in the learning process. visual-spatial and visual analysis skills are components of the visual motor skill. any deficiency in visual-motor skills and their components often causes problem in writing and learning processes in children. the aim of this study was to investigate the effect of occupational therapy (o.t.) intervention on...

diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. aegle marmelos corr. from rutaceae family, is widely used in iranian folk medicine for the treatment of diabetes mellitus. it decreases blood glucose level by improving glucose tolerance and also has lipid-lowering and antioxidant properties. considering the beneficial antidiabetic potential of a...