Despite the remarkable advance in medicine and science, the complete cure of neuropsychiatric disorders is still a challenging task. In the aging society, the prevalence of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease has rapidly been increased. The complex relationship of the community members induces serious mental diseases including depression. Increment in ...

Objective(s): It is known that treadmill exercise has   beneficial effects on the nervous system. The brain-derived neurotrophic factor (BDNF) plays a role in such effects. This study aimed at investigating effects of intermittent treadmill exercise-induced behavioral, histology, and immunohistochemistry (H&E;, TH) measurement of brain interleukin-10 (IL-10) in a mice m...

[Purpose] A stationary bicycle exercise and a treadmill exercise were conducted in order to determine the effect of these exercises on the balance and walking ability of elderly women. [Subjects and Methods] Twenty-four elderly women aged 65 or older were equally assigned to a stationary bicycle exercise group and a treadmill exercise group, and they performed exercise three times per week for ...

in recent years, the effects of exercise on nervous system, spatial memory andmotor function in the senescence period have received the attention of researchers.as the age increases, some functions of nervous system such as spatial memory areweakened. thus, the effect of aerobic exercises including swimming and runningon learning, spatial memory and motor function was investigated in old rats. ...

[Purpose] In the present study, we hypothesized that exercise of the nonaffected forelimb in the early poststroke phase would stimulate the intact hemisphere, thereby influencing the hemisphere of the infarcted side and improving the performance of the hemiplegic limb. [Subjects and Methods] Adult male Sprague-Dawley rats (8-10 weeks of age, weighing 250-300 g, n=12) were used and randomly divi...

Autism is a complex developmental disorder with impairments in social interaction, communication, repetitive behavior and motor skills. Exercise enhances cognitive function, ameliorates motor dysfunction, and provides protective profits against neurodegeneration. In the present study, we evaluated the effect of treadmill exercise on the motor coordination and Purkinje cell loss in relation with...

Moderate aerobic exercise has been shown to enhance motor skills and protect the nervous system from neurodegenerative diseases, like ataxia. Our lab uses the spastic Han Wistar rat as a model of ataxia. Mutant rats develop forelimb tremor and hind limb rigidity and have a decreased lifespan. Our lab has shown that exercise reduced Purkinje cell degeneration and delayed motor dysfunction, signi...

Acute cognitive benefits, such as temporary improvements in concentration, can result from as few as ten minutes of exercise; however, most people do not take exercise breaks throughout the day. To motivate people to receive the cognitive benefits of exercising in short bursts multiple times per day, we designed an engaging casual exergame. To determine whether there are cognitive benefits afte...