Fig. 1. Sodium dodecyl sulfate/polyacrylamide gel electrophoresis study of the urinary proteins of eight diabetic patients The first two gels on the left were used to separate reference proteins. Ingel C we separated several ptxifled proteins of known molecular weiits: 1gM(1 000 000), igG(153 000), transfenin (17?.76 000), senan albumin (ALB, 66 000), egg albumin (OVA,46 000), thymotrypsinogen ...

Multiple myeloma was diagnosed in six residents of Thief River Falls, Minn. in 1968 (a rate of 84/100,000). A survey of the normal population for monoclonal serum protein peaks was undertaken in 1969. Serum from 1200 residents of the city, who were 50 yr of age or older, was collected. Fifteen (1.25#{176}/o) had monoclonal serum protein peaks: lgG in 11, IgA in one, and 1gM In three, with kappa...

C HRONIC LYMPHOCYTIC LEUKEMIA (CLL) B cells are, in general, highly refractory to transformation by Epstein-Barr virus (EBV),’ and therefore, relatively few EBV-immortalized cell lines originating from CLL cells have been described.’4 In this paper we report the establishment of a novel EBV-transformed B cell line from the leukemic cells of a CLL patient that expressed surface u immunoglobulin....

Thrombotic thrombocytopenic purpura endothelium and in thrombi in small (UP) is a disorder of unknown etiblood vessels in multiple organs. ology. An immunologic basis has been These findings suggest an active imsuggested, although proof is lacking. munologic process in this case. While The immunologic, hematologic, and UP is probably of diverse etiology, autopsy findings in a case of TTP occonf...

Previous studies in Ghana and the United States have shown that the great majority of primary Epstein-Barr virus (EBV) infections in infants remain silent and fail to evoke hematologic and heterophil antibody responses typical of infectious mononucleosis (lM). In the present study. a search was made for cases of IM among children less than age 49 mo and a diagnosis of this disease was made in 3...