AIM To analyze the neurotoxic potential of synthesized magnetite nanoparticles coated by dextran, hydroxyethyl starch, oxidized hydroxyethyl starch, and chitosan, and magnetic nanoparticles combined with ferritin as a native protein. METHODS The size of nanoparticles was analyzed using photon correlation spectroscopy, their effects on the conductance of planar lipid membrane by planar lipid b...

Mesoporous silica nanoparticles (MSNPs) have garnered a great deal of attention as potential carriers for therapeutic payloads. However, achieving triggered drug release from MSNPs in vivo has been challenging. Here, we describe the synthesis of stimulus-responsive polymer-coated MSNPs and the loading of therapeutics into both the core and shell domains. We characterize MSNP drug-eluting proper...

In this article, we present an efficient synthesis pathway of polydimethylsiloxane (PDMS) coated magnetic nanoparticles from hydrophilic polyacrylate coated ferrofluids (NPPAA). A block copolymer based on polydimethylsiloxane is selected for its propensity to interact with the carboxylate functions on the NPPAA. The interaction is due to negative charges on NPPAA and positive ones on the amphip...

Present review article describes main causes of chronic kidney disease a major health problem public health problem round the globe. Disease has multiple etiologies related to sequential pathophysiological stages. It has major concern with chronic changes in renal structure and that severely alter glomerular filtration rate in patients. This article explains CKD biomarkers in brief i.e., serum ...

Ultrasmall glutathione-coated luminescent gold nanoparticles (GS-AuNPs) are known for their high resistance to serum protein adsorption. Our studies show that these NPs can serve as surface ligands to significantly enhance the physiological stability and lower the serum protein adsorption of superparamagnetic iron oxide nanoparticles (SPIONs), in addition to rendering the NPs the luminescence p...

Here we present a simple and controlled method for direct fabrication of ordered 2D arrays of magnetic rings. This method utilizes polystyrene-coated magnetite nanoparticles as a solution, and the magnetic rings are fabricated on patterned self-assembled monolayers by dewetting of the solution. Polystyrene-coated magnetite nanoparticles were synthesized by atom-transfer radical polymerization, ...

Hybrid magnetic/plasmonic nanoparticles possess properties originating from each individual material. Such properties are beneficial for biological applications including bio-imaging, targeted drug delivery, in vivo diagnosis and therapy. Limitations regarding their stability and toxicity, however, challenge their safe use. Here, the one-step flame synthesis of composite SiO2-coated Ag/Fe2O3 na...

Two optimized strategies were successfully established to develop biomolecule-based magnetic nanoassemblies. Streptavidin-coated and amine-coated magnetic nanoparticles were chosen as model scaffolds onto which double-stranded DNA and human immunoglobulin G were specifically conjugated in succession, using biotin-streptavidin interaction or covalent cross-linkers. The success of this study open...

This communication describes the co-assembly of polydopamine spheres, either bare or coated with Fe3O4 magnetic nanoparticles, with the short aromatic peptide diphenylalanine. The combination of polydopamine particles and diphenylalanine generated tubular structures decorated with adhesive spherical particles, while the co-assembly of the polydopamine spheres coated with magnetic Fe3O4 nanopart...