literature review shows that hepatitis c infection may increase the risk of non-hodgkin lymphoma. reactivation of hepatitis b infection has been reported in patients with hairy cell leukemia after chemotherapy and/or splenectomy. we present hepatitis b surface (hbs) antigenemia and concurrent hepatitis c virus (hcv) seropositivity in a case of hairy cell leukemia. key words: hairy cell leukemia...

Background and Aims: DNA methyltransferase3A (DNMT3A) is necessary for the adjustment of gene expression, and the mutations in the DNMT3A gene are reported in a variety of leukemia cases. DNMT3A mutations are during cancer progression and cause poor prognosis in many leukemias. Thus, this gene can be a target for new treatments. This study aimed to examine the distribution of DNMT3A mutations i...

a 61-year-old female presented with complaints of fever, general weakness and hepatosplenomegaly. she had a history of nonfamilial peripheral neurofibromatosis diagnosed as von recklinghausen's disease since 30 years previous. physical examination was remarkable for skin colored cutaneous circumscribed nodules which appeared soft to the touch in both arms, the upper part of her abdomen, back, a...

background: cancer is the third most common cause of death in iran, the leukemia cancer is one of the most important causes of cancer mortality. regarding cancer mortality, data would be important to monitor the program screening effects, earlier diagnosis, demographic data and other prognostic factors. the aim of this study was mortality rates evaluating, then leukemia cancer trends among the ...

background: acute myeloid leukemia (aml) with translocation (3,3) is a form of aml that may present de novo or may arise from a previous myelodysplastic syndrome. it is often associated with normal or elevated peripheral blood platelet count and increased bone marrow megakaryocytes with associated multi lineage dysplasia. a subset of patients present with hepatosplenomegaly while a few cases ha...

Background: Patients with leukemia are facing more complications in order to achieve longer survival. We aimed to evaluate the frequency of central nervous system abnormalities (CNS) on MRI of children with acute lymphoblastic leukemia (ALL). Methods: Sixty-six children with diagnosis of ALL aged 2-18 years were recruited. Non-contrast sequences of brain MRI in addition to diffusion weighted i...

incidence of infertility is 15-20%. tubal and peritontal factors are responsible for 30-40% of infertility cases. in evaluation of infertile women, hysterosalpingography (hsg) is the first test in evaluating of fallopian tubes and laparoscopy is the gold standard test for diagnosing tubal problems and pelvic adhesions. in this study we evaluated 291 infertile couples. study is prospective, desc...