In this paper, a stochastic programming approach is applied to the airline network revenue management problem. The airline network with the arc capacitated single hub location problem based on complete–star p-hub network is considered. We try to maximize the profit of the transportation company by choosing the best hub locations and network topology, applying revenue management techniques to al...

This study investigated the effect of silane and surfactant treatments of graphene nanoplatelets (GnPs) on the mechanical and thermal properties of silicone rubber (SR) composites. GnPs were modified with aminopropyltriethoxysilane (APTES), vinyltrimethoxysilane (VTMS), and Triton X-100, and then the pristine GnPs and functionalized GnPs were individually incorporated into the SR. Compared with...

BACKGROUND & OBJECTIVES Increased severity of osteoarthritis (OA) and adverse side effects of its treatment led to the search for alternative therapies. It was previously reported that snake venom protein toxin Naja kaouthia cytotoxin 1 (NKCT1) and gold nanoparticle (GNP) individually have potential against excremental arthritis. In this study, we analyzed the protective activity of GNP conjuga...

Graphene nanoplatelets (GNPs) are added as reinforcement to ultrahigh molecular weight polyethylene (UHMWPE) with an intended application for orthopedic implants. Electrostatic spraying is established as a potential fabrication method for synthesizing large-scale UHMWPE-GNP composite films. At a low concentration of 0.1 wt % GNP, the composite film shows highest improvement in fracture toughnes...

Nanoscience and Nanotechnology have found their way in the fields of pharmacology and medicine. The conjugation of drug to nanoparticles combines the properties of both. In this study, gold nanoparticle (GNP) was conjugated with NKCT1, a cytotoxic protein toxin from Indian cobra venom for evaluation of anti-arthritic activity and toxicity in experimental animal models. GNP conjugated NKCT1 (GNP...

Recent work has demonstrated that genetic programming is capable of automatically creating complex networks (such as analog electrical circuits and controllers) whose behavior is modeled by continuous-time differential equations (both linear and nonlinear) and whose behavior matches prespecified output values. The concentrations of substances participating in networks of chemical reactions are ...

Aims : To investigate the toxic effect of gold nanoparticles (GNPs) to the learning and memory of mice. Main methods: Naked GNPs of 17 nm and 37 nm were synthesized, purified, and injected intraperitoneally into BALB/C mice at a dose of 8 mg/kg/week. Passive avoidance test was performed to detect the possible leaning impairment. Biochemical analysis to examine levels of monoamine and acetylchol...

in this research, we address the application of uncertaintyprogramming to design a multi-site, multi-product, multi-period,closed-loop supply chain (clsc) network. in order to make theresults of this article more realistic, a clsc for a case study inthe iron and steel industry has been explored. the presentedsupply chain covers three objective functions: maximization ofprofit, minimization of n...