نتایج جستجو برای: hepatitis c virus
تعداد نتایج: 1441599 فیلتر نتایج به سال:
background macrophages play critical roles in innate immune response in the liver. whether macrophages participate in liver innate immunity against hcv replication is poorly understood objectives the aim of this study was to investigate the role of macrophages in liver innate immunity against hcv replication. conclusions macrophages may play an important role in liver innate immunity against hc...
Following interferon-based therapy for chronic hepatitis C, the negativity of hepatitis C virus RNA is essential to achieve viral clearance at the end of treatment. We report a case of clearance of chronic hepatitis C virus infection following early discontinuation (at 6 weeks) of peginterferon plus ribavirin therapy, without negativity for hepatitis C virus RNA during the treatment period. The...
Hepatitis C virus (HCV) infection has affected approximately 180 million people across the world. In most cases, HCV-infection remains chronic, which expose patients at high risk of cirrhosis and hepatocellular carcinoma. The rates of disease incidence and mortality diminish as a result of successful treatment of HCV infection. Until the recent years, despite the associated toxicities and l...
Background and Objective: The prevalence of hepatitis C infection is less than 1% in the general population, however the trend is increasing. Little is known about epidemiology of hepatitis C in Yazd according to population based data. This study was conducted to investigate the epidemiology of hepatitis C in Yazd during 2010-2012. Materials and Methods: This was a cross-sectional...
background hepatitis c virus (hcv) infection is the most significant source of chronic liver diseases in the globe. about 170 million individuals are infected by hcv worldwide. the reported prevalence of hcv in different areas of khyber pakhtunkhwa (kp) ranges from 4.1 to 36%. objectives the current study aimed to analyze the true prevalence of hcv infection in khyber pakhtunkhwa, pakistan. mat...
conclusions hcv gpe2 is an ideal target for hcv vaccine. prediction of epitope immunogenicity and characterization on the basis of peptide sequences will be significantly helpful for development of a heterologous vaccine against hcv variants. results many b-cell and t-cell epitopes predicted in gpe2 were found conserved among hcv 3a genotypes whereas few were conserved in other genotypes antici...
background the hepatitis c virus (hcv) infection has been identified as a leading cause of progressive liver diseases worldwide. despite new treatment strategies, pegylated interferon alfa-2a (peg-ifnα-2a), in combination with ribavirin (rbv), still represents the gold standard of therapy for hepatitis c in developing countries. results in this study, a significant association was observed betw...
conclusions polymorphism in the hemochromatosis gene may confer some degree of risk for hcv infection, and individuals carrying the h and c alleles may be susceptible to this disease; however, a larger sample of hcv patients and healthy individuals may be necessary to further illustrate the role of these polymorphisms in hcv. patients and methods hfe gene polymorphisms were examined in a total ...
normal 0 false false false en-us x-none ar-sa background: hepatitis c virus (hcv) is the main causative agent of post-transfusion hepatitis. the virus is distributed worldwide with varying prevalence in different countries, which could easily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma. the aim of this study was to investigate prevalence of hcv infection and its tre...
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