approximately 25% of all oral cavity carcinomas involve the lips, and the primary management of these lesions is complete surgical resection. loss of tissue in the lips after resection is treated with a variety of techniques, depending on the extension and location of the defect. here we review highly accepted techniques of lip reconstruction and some of new trials with significant clinical res...

In HeLa cells depleted of adaptor protein 2 complex (AP2) by small interfering RNA (siRNA) to the mu2 or alpha subunit or by transient overexpression of an AP2 sequestering mutant of Eps15, endocytosis of the transferrin receptor (TfR) was strongly inhibited. However, epidermal growth factor (EGF)-induced endocytosis of the EGF receptor (EGFR) was inhibited only in cells where the alpha subunit...

River bed sand and gravel are utilized more than mountain materials due to their availability and closeness to the transit roads and sites of usage. Excessive and non-technical extraction of gravel and sand bring a kind of interference in them, leading to many negative consequences. Therefore, presenting solutions to reduce these impacts and infilling mining pits are essential. In this researc...

The capture of patchily distributed nutrients by tree roots has received extensive research, but the fate of those nutrients has not. We performed experiments to determine if nutrient transport within tree species is preferentially transported from specific roots to specific branches. Saplings of five species with contrasting growth requirements were examined: two Betula species (B. papyrifera ...

Members of the Cryptochiridae are small, fragile, symbiotic crabs that live in domiciles in modern corals. Despite their worldwide occurrence with over 50 species known today, their fossil record is unknown. We provide the first unambiguous evidence of cryptochirids in the fossil record through their crescentic pits, typical for certain cryptochirids, in Western Atlantic fossil corals, while th...

Phylogenetic relationships of the Antiperyphanes Complex of the genus Bembidion are inferred using DNA sequences from seven genes (two nuclear ribosomal, four nuclear protein coding, and one mitochondrial protein coding). Redefined subgenera within the complex are each well-supported as monophyletic. Most striking was the discovery that a small set of morphologically and ecologically heterogene...

We previously demonstrated, using fluorescence recovery after photobleaching, that clathrin in clathrin-coated pits at the plasma membrane exchanges with free clathrin in the cytosol, suggesting that clathrin-coated pits are dynamic structures. We now investigated whether clathrin at the trans-Golgi network as well as the clathrin adaptors AP2 and AP1 in clathrin-coated pits at the plasma membr...