Tumor suppressor protein p53 is a transcription factor that plays important roles in biological responses to a wide range of ionizing radiation doses. Elucidation of the molecular mechanisms for its function after actually relevant doses of radiation is therefore crucial for the accurate understanding of the biological effects of radiation. p21 is one of the p53 target genes, functioning in cel...

We developed a web application for crowdsourcing transcriptions of Dutch words spoken by Spanish L2 learners. In this paper we discuss the design of the application and the influence of metadata and various forms of feedback. Useful data were obtained from 159 participants, with an average of over 20 transcriptions per item, which seems a satisfactory result for this type of research. Informing...

introduction: the purpose of this study was determine the application of knowledge management among the staff members of central, faculty, and hospital libraries at tabriz university of medical sciences (tabriz, iran), based on hissig model. hissig model consists of four processes including knowledge creation, storage, sharing, and application. methods: this descriptive survey included all of t...

In Medtronic, Inc. v. Lohr, the United States Supreme Court, in a five-to-four split, held that the Medical Device Amendments of 1976 did not preempt state tort claims against a pacemaker manufacturer. A careful reading of the factually specific holding of this case suggests that manufacturers of medical devices distributed pursuant to premarket approval requirements and investigational device ...

Image classification and retrieval systems have gained more attention because of easier access to high-tech medical imaging. However, the lack of availability of large-scaled balanced labelled data in medicine is still a challenge. Simplicity, practicality, efficiency, and effectiveness are the main targets in medical domain. To achieve these goals, Radon transformation, which is a well-known t...

Received: July 12, 2015 Revised: September 17, 2016 Accepted: September 17, 2016 Abstract: Introduction: With the rise of computer technology, there has seen a shift in the delivery of medical education towards e-learning. Specifically, there has been increased use smartphone technology and applications (app) use. Aim: The aim of this article is to assess the use of medical apps amongst medical...

The concept of a compact ion particle accelerator has become attractive in view of recent progress in laserdriven ion acceleration. We report here the recent progress in the laser-driven proton beam transport at the Photo Medical Research Center (PMRC) at JAEA, which is established to address the challenge of laser-driven ion accelerator development for ion beam cancer therapy.

At iThemba Labs, we are constructing a patient positioning system for proton therapy. This system will use stereo vision techniques to accurately position the patient relative to the beam line. To do this, we need to be sure that the vision system is functioning correctly. In addition to various procedural checks, we implement a variety of software tests to try and detect errors in the vision s...