The nanotechnology revolution has allowed us to speculate on the possibility of hybridising nanoscale materials with live substrates, yet significant doubt still remains pertaining to the effects of nanomaterials on biological matter. In this investigation, we cultivate the ciliated protistic pond-dwelling microorganism Paramecium caudatum in the presence of excessive quantities of magnetite na...

Multifunctional core-shell nanocomposites with a magnetic core and a silica shell doped with lanthanide chelate have been prepared by a simple method. First, citric acid-modified magnetite nanoparticles were synthesized by a chemical coprecipitation method. Then the magnetite nanoparticles were coated with silica shells doped with terbium (Tb(3+)) complex by a modified Stöber method based on hy...

In the work the thermal behaviour of the magnetic nanoparticles modi ed with polysaccharide dextran of di erent weight ratios to the magnetite Fe3O4 was investigated using thermoanalytical methods di erential scanning calorimetry and thermogravimetric analysis. The adsorption of dextran on the magnetic nanoparticles was con rmed and the in uence of the dextran amount in the modi ed magnetic uid...

In order to develop melanoma-targeted in situ peptide vaccine immunotherapy, magnetite nanoparticles were conjugated with a melanogenesis substrate, N-propionyl cysteaminylphenol (NPrCAP). Magnetite nanoparticles introduced thermotherapy which caused non-apoptotic cell death and generation of heat shock protein (HSP) upon exposure to alternating magnetic field (AMF). NPrCAP was expected to deve...

We demonstrate a new design concept where the interaction between silica nanoparticles (about 1.5 nm in diameter) with titania nanoparticles (anatase, about 4 nm or 6 nm in diameter) guides a successful formation of mesoporous titania with crystalline walls and controllable porosity. At an appropriate solution pH (~1.5, depending on the deprotonation tendencies of two types of nanoparticles), t...

We report the synthesis of Fe3O4@mSiO2 nanostructures of different meso-silica (mSiO2) shell thickness, their biocompatibility and behaviors for loading and release of a model drug ibuprofen. The composite nanostructures have superparamagnetic magnetite cores of 208 nm average size and meso-silica shells of 15 to 40 nm thickness. A modified Stöber method was used to grow the meso-silica shells ...

Magnetite is an iron oxide found in rocks. Its magnetic properties are used for paleoclimatic reconstructions. It can also be synthesized in the laboratory to exploit its magnetic properties for bio- and nanotechnological applications. However, although the magnetic properties depend on particle size in a well-understood manner, they also depend on the structure of the oxide, because magnetite ...

Surface-enhanced Raman spectroscopy (SERS) of species bound to environmentally relevant oxide nanoparticles is largely limited to organic molecules structurally related to catechol that facilitate a chemical enhancement of the Raman signal. Here, we report that magnetite (Fe3O4) nanoparticles provide a SERS signal from oxalic acid and cysteine via an electric field enhancement. Magnetite thus l...

The present study synthesizes a novel adsorbent by coating Fe3O4 magnetic nanoparticles with amino functionalized mesoporous silica. The FTIR spectrums indicate that silica has been successfully coated on the surface of Fe3O4 and 3-aminopropyl tri methoxysilane compound have been grafted to the surface of silica-coated Fe3O4. The XRD analysis shows the presence of magnetite phase with cubic spi...

In this work, we report a portable microfluidic chip based on Si-Porous-Pt MSNs(Mesoporous Silica Nanoparticles) -enhanced electrochemical detection for single-bacteria diognostic. The possibility of single-bacteria detection is realized here by using electroactive molecules modified on Si-Porous-Pt MSNs(Mesoporous Silica Nanoparticles) to detect and differentiate Staphylococcus aureus and Pseu...