Oxidative stress is a phenomenon caused by an imbalance of peroxide homeostasis. The concept oxidative was introduced in 1985 and has clear connection with redox chemistry. article provides detailed description molecular switches that control the response to stress. Four levels protection cell enzymatic antioxidants from action reactive oxygen species are described. It been shown antioxidant en...

Type 1 diabetes is a chronic disease characterized by the body's inability to produce insulin due to destruction of the beta cells. There is increasing evidence that reactive oxygen species (ROS) play a major role in the development of diabetic complications. The purpose of this study is to investigate the effects of troxerutin administration on oxidative stress markers in blood of STZ-induced ...

Methamphetamine (MET) is a stimulant and one of the most abused drugs in worldwide. MET could cause several organ toxicity such as cardiotoxicity. Oxidative stress has been proposed as the main mechanism for MET toxicity. Propofol as a sedative-hypnotic agent has antioxidant property. In this study, we used propofol for attenuating of MET-induced cardiotoxicity in rats. The groups (six rats in ...

Oxidative stress Hemodialysis Malondialdehyde Antioxidant enzymes Free Radicals.

The mechanism underlying the action of lignocellulolytic enzymes in biodegradation of lignocellulosic biomass remains unclear; hence, it is crucial to investigate enzymatic interactions involved in the process. In this study, degradation of corn cob by Sporothrix carnis and involvement of lignocellulolytic enzymes in biodegradation were investigated over 240 h cultivation period. About 60% degr...

Objective(s) The aim of this study was to evaluate the effects of regular exercise in preventing diabetes complication in the hippocampus of streptozotocin (STZ)-induced diabetic rat. Materials and Methods A total of 48 male wistar rats were divided into four groups (control, control exercise, diabetic and diabetic exercise). Diabetes was induced by injection of single dose of STZ. Exercise ...

The present study focuses on the role of Costus pictus extract (CPE) against the oxidative stress caused by hypeglycemia in liver and kidney of alloxon administered rats.Hyperglycemic rats were administered with two dose levels(200 and 400mg/kg body weight) of CPE for 30 days.At the end of treatment,blood glucose,serum marker enzymes alanine amino transfrease(ALT),aspartate amino transferase(AS...

NADPH oxidase (NOX2) is a multisubunit membrane-bound enzyme complex that, upon assembly in activated cells, catalyses the reduction of free oxygen to its superoxide anion, which further leads to reactive oxygen species (ROS) that are toxic to invading pathogens, for example, the fungus Aspergillus fumigatus. Polymorphonuclear cells (PMNs) employ both nonoxidative and oxidative mechanisms to cl...