A bisphenol A production plant possesses considerable potential risks in the top of the methanol separation column, as pressurized acetone, methanol, and water are processed at an elevated temperature, especially in the event of an abnormal pressure increase due to a sudden power outage. This study assesses the potential risks in the methanol separation column through hazard and operability ass...

Point mutations and small insertions or deletions in the human alpha-globin genes may produce alpha-chain structural variants and alpha-thalassemia. Mutations can be detected either by direct DNA sequencing or by screening methods, which select the mutated exon for sequencing. Although small (about 1 kb, 3 exons and 2 introns), the alpha-globin genes are duplicate (alpha2 and alpha1) and highly...

We study the problem of computing isochrones in road networks, where the objective is to identify the region that is reachable from a given source within a certain amount of time. While there is a wide range of practical applications for this problem (e. g., reachability analyses, geomarketing, visualizing the cruising range of a vehicle), there has been little research on fast computation of i...

PURPOSE We compared phospholipid (phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, and phosphatidylinositol) profiles of control and glaucomatous trabecular meshwork (TM) derived from human donors. METHODS Control TM and most primary open angle glaucoma (POAG) TM were collected from cadaver donors. A select subset of POAG surgical TM samples also were collected for analyses....

Essential genes are thought to encode proteins that carry out the basic functions to sustain a cellular life, and genomic islands (GIs) usually contain clusters of horizontally transferred genes. It has been assumed that essential genes are not likely to be located in GIs, but systematical analysis of essential genes in GIs has not been explored before. Here, we have analyzed the essential gene...