نتایج جستجو برای: rippening 504 and early
تعداد نتایج: 16926422 فیلتر نتایج به سال:
I. Protein folding in the cell. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494 II. Molecular and chemical chaperones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494 A. Heat shock response and heat shock proteins . . . . . . . . . . . . . . . . . ...
Targeting Hsp90 is an attractive strategy for anticancer therapy because the diversity and relevance of biological processes are regulated by these proteins in most cancers. However, the role and mode of action of Hsp90 inhibitors in pancreatic cancer has not been studied. This study aimed to assess the antitumor activity of the Hsp90 inhibitor, IPI-504, in pancreatic cancer and to determine th...
PURPOSE Gliomas are the most common primary intracranial tumors of the central nervous system (CNS), accounting for about one third of all brain tumors. Glioblastoma multiforme (GBM) is the aggressive grade IV glioma with survival as low as 2-5% in the second year post-diagnosis, hence necessitating efficient diagnostic markers. More than 50% of the non-small cell lung cancer (NSCLC) brain meta...
بررسی تنوع ژنتیکی ژنوتیپهای بومی پیاز ایرانی در مقایسه با انواع خارجی چکیده: برنامه های اصلاحی گیاهان بر اساس تنوع و انتخاب صفات برتر کمی و کیفی صورت می گیرد. لذا، ارزیابی تنوع ژنتیکی، اولین مرحله در برنامه های اصلاحی است. در این راستا، استفاده از روش های جدید مطالعهی تنوع ژنتیکی ضروری به نظر می رسد. در این بررسی تعیین تنوع ژنتیکی سیزده ژنوتیپ پیاز ایرانی در مقایسه با دو ژنوتیپ خارجی با است...
Background and purpose: Recently, a high rate of cutaneous leishmaniasis (CL) has been reported in Torbat-e-Jam a town in Khorasan Razavi province, Iran. The aim of the present study was to investigate the epidemiological aspects of CL in this district. Materials and methods: This descriptive cross-sectional study was carried out in patients referring to health centers of Torbat-e-Jam, during ...
The issue of heterozygosity continues to be a challenge in the analysis of genome sequences. In this article, we describe the use of allele ratios to distinguish biologically significant single-nucleotide variants from background noise. An application of this approach is the identification of lethal mutations in Caenorhabditis elegans essential genes, which must be maintained by the presence of...
The HSV-1 alpha (immediate-early) protein ICP27 expressed in transfected cells can activate the expression of certain HSV-1 promoters as well as inhibit the transactivated expression of others. We constructed a set of plasmids encoding mutant ICP27 molecules truncated at their carboxyl termini and used transfection assays to determine the functional properties of the mutant proteins. A polypept...
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