نتایج جستجو برای: tissue expression
تعداد نتایج: 1613066 فیلتر نتایج به سال:
introduction: failure of human body tissue and organs is believed to be one of the most important health problems all over the world. the great challenge for tissue engineers is to optimize suitable systems to separate, proliferate and differentiate the cells so that they can set out to create tissue by a harmonic 3-d growth. therefore, the tissue engineers must provide an environment like the ...
BACKGROUND Dedifferentiation of chondrocytes remains a major problem for cartilage tissue engineering. Chondrocytes loss differentiated phenotype in in vitro culture that is undesired for repair strategies. The chondrocyte is surrounded by a pericellular matrix (PCM), together forming the chondron. PCM has a positive effect on the maintenance of chondrocyte phenotype during culture in compar...
Background and Objective: Mesenchymal stem cells are promising sources of stem cells for tissue repair because of their ability to differentiate into different cells, easy proliferation and culture, and immunomodulatory properties. Despite extensive research on the immunophenotype of mesenchymal stem cells, a lack of specific markers comprises challenges for researchers. The aim of this researc...
Background and purpose: Chronic non-healing diabetic wounds are a major medical challenge worldwide. Stem cell therapy has been developed as a new approach in the management of such wounds that need to be explored further. In the present study we aimed to evaluate the effects of adipose derived mesenchymal stem cells (ADSCs) on gene expression level of some important inflammatory factors involv...
Background: Two of the Wnt signaling pathway target genes, tumor necrosis factor receptor family member (TROY) and leucine-rich G-protein coupled receptor (LGR5), are involved in the generation and maintenance of gastrointestinal epithelium. A negative modulatory role has recently been assigned to TROY, in this pathway. Here, we have examined their simultaneous expression in gastric carcinogene...
Background In vitro culturing and retransplantion of vitrified- warmed ovarian tissue are two ways to restore fertility after radiation or chemotherapy.This study aimed to evaluate the incidence of apoptosis in vitrified human ovarian tissue after warming, long term culturing and xenotransplantation by morphological analyses and apoptosis genes expression evaluation. MaterialsAndMethods We obta...
Background & Objective: Angiopoietin-like Proteins 8 (ANGPTL8) which secreted form adipose tissue due to downstream PGC-1α pathways, is the main factor for regeneration of beta cell. The aim of this study was to investigate the effect of 4 endurance training program on PGC-1α expression in adipose tissue, ANGPTL8 serum concentration and beta cell function (HOMA.B) in diabetic rats. Materials & ...
The importance of mesenchymal stem cells (MSCs), as adult stem cells (ASCs) able to divide into a variety of different cells is of utmost importance for stem cell researches. In this study, the ability of cartilage extract to induce differentiation of rat derived omentum tissue MSCs (rOT-MSCs) into chondrocyte cells (CCs) was investigated. After isolation of rOT-MSCs, they were co-cultured with...
BACKGROUND Mesenchymal stem cells (MSCs) are ideal candidates for treatment of diseases. Amniotic membranes are an inexpensive source of MSCs (AM-MSC) without any donor site morbidity in cell therapy. Adipose tissue derived stem cells (ASCs) are also suitable cells for cell therapy. There is discrepancy in CD271 expression among MSCs from different sources. In this study, the characteristics...
The studies about the effect of exercise training on expression of Uncoupling Protein 1 (UCP-1) in different adipose depots were few. Thus, the purpose of this study was to investigate the effect of eight weeks endurance training on expression of this gene in retroperitoneal adipose tissue of wistar rats. Methods: 20 rats were purchased, and were divided randomly into two g...
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