background: type 1 diabetes (t1d) is caused by cell-mediated autoimmune attack on pancreatic beta-cells. previous studies highlight the role of micrornas (mirnas) in the pathogenesis of t1d. mirnas are small non-coding rnas involved in the regulation of gene expression post-transcriptionally. in this work, mir-18b was chosen and the differential expression of it was measured between t1d patient...

micro-rnas are a large group of non-coding rnas with 18-25 nucleotides. polymorphisms in the human pre-mir-rna could change the efficiency of target cell and can also play a role in cell cycle regulation and cancer. the aim of this study was to investigate the association of rs11614913 t/c polymorphism with gastric cancer risk in ardabil province. in a case-control study, this polymorphism was ...

Background: Type 1 diabetes (T1D) is caused by cell-mediated autoimmune attack on pancreatic beta-cells. Previous studies highlight the role of microRNAs (miRNAs) in the pathogenesis of T1D. MiRNAs are small non-coding RNAs involved in the regulation of gene expression post-transcriptionally. In this work, miR-18b was chosen and the differential expression of it was measured between T1D patient...

Meat inspection records in abattoirs located in Torbat-e-heidarieh (northeast Iran), from 18 May 2009 to 30 May 2015, were used to determine the prevalence of liver fluke diseases in sheep and cattle in the region. A total of 1004858 livestock including 867015 sheep and 137843 cattle were slaughtered in the 6-year period. Dicrocoeliosis, fasciolosis and hydatidosis were responsible for 2%, 1.92...

background: transient elastography (te) is a new modality for the diagnosis of liver fibrosis caused by various etiologies. this study was conducted to determine the accuracy of te in detecting the different stages of liver fibrosis in non-alcoholic fatty liver disease (nafld) patients. methods: medline/pubmed, embase, ovid, cochrane library, american college of physicians (acp) journal club, g...

Introduction:  Microalgae  are  known  for  their  bioactive  compounds  with  potential applications as antimicrobial, antiaging, and anticancer activities. Spirulina platensis (S. platensis) is a filamentous and photosynthetic microorganism that has 25 kinds of vitamins and minerals that contain many compounds with biotic activity such as alkaloids, phenolic compounds, terpenoids, and saponin...

Here for the first time, we investigated the cytotoxic effects of the chitosan extracted from the Persian Gulf Chiton shell (Acanthopleura vaillantii) on liver cancer cell line (HepG2). Chitosan extraction was implemented following this method: chitin was produced by demineralization and deproteinization procedure, and the extracted chitin was converted into soluble chitosan using deacetylation...