Article history: Received August 19, 2011 Received in Revised form November, 11, 2011 Accepted 12 November 2011 Available online 18 November 2011 We present an empirical study to study the effects of different factors on juvenile delinquency. The investigation distributes 100 questionnaires among people who are involved with crime and analyzes their feedbacks. There are five hypotheses in our s...

BACKGROUND Adult-onset stressors exert opposing effects on hippocampal neurogenesis and cognition, with enhancement observed following mild stress and dysfunction following severe chronic stress. While early life stress evokes persistent changes in anxiety, it is unknown whether early stress differentially regulates hippocampal neurogenesis, trophic factor expression, and cognition across the l...

Important aspects of plant development are under epigenetic control, that is, under the control of heritable changes in gene expression that are not associated with alterations in DNA sequence. It is becoming clear that RNA molecules play a key role in epigenetic gene regulation by providing sequence specificity for the targeting of developmentally important genes. RNA-based control of gene exp...

The enzyme-catalyzed acetylation of the N-terminal tail domains of core histones provides a rich potential source of epigenetic information. This may be used both to mediate transient changes in transcription, through modification of promoter-proximal nucleosomes, and for the longer-term maintenance and modulation of patterns of gene expression. The latter may be achieved by setting specific pa...

The severe adverse effects of gonococcal infection on human fertility suggests that Neisseria gonorrhoeae would exert powerful selection for the development of a protective immune response in humans. N. gonorrhoeae is an obligate human pathogen and must persist in humans to survive. Since it is an ecologically successful organism, it must have evolved strategies to evade any human immune respon...

Although carcinogenic metals have been known to disrupt a wide range of cellular processes the precise mechanism by which these exert their carcinogenic effects is not known. Over the last decade or two, studies in the field of metal carcinogenesis suggest that epigenetic mechanisms may play a role in metal-induced carcinogenesis. In this review we summarize the evidence demonstrating that expo...

Early experiences can modify regulatory factors affecting gene expression in such a way that, although the DNA sequence itself is not changed, the individual's physiology and behavior is substantially influenced. In some instances these epigenetic effects are exerted upon exposure, while in other instances they are transmitted across generations via incorporation into the germline. Examples of ...