background aflatoxins are one of the most potent toxic substances that occur naturally. nowadays extensive attention has been taken to their existence in food and environment, as there is the possibility of harm to humans following chronic exposure to extremely low levels via food chain. aflatoxin m1 (afm1) is a hepatic carcinogenic metabolite found in the milk of lactating animals fed with con...

BACKGROUND Although aflatoxin exposure has been associated with micronutrient deficiency in animals, there are few investigations on the effects of aflatoxin exposure on micronutrient metabolism in humans. OBJECTIVE To examine the relationship between aflatoxin B1 (AFB1) albumin adducts (AF-ALB) in plasma and the aflatoxin M1 (AFM1) metabolite in urine and plasma concentrations of retinol (vi...

background: aflatoxins are found in the most types of foods such as corn, peanuts, pistachio, rice, milk, and etc. these toxins may cause several adverse health effects, notably cancer. the main aim of this study was to evaluate excretion level of aflatoxin m1 (afm1), as a biomarker of aflatoxin b1 exposure, in urine samples of iranian population. also, relationship between diet and urinary exc...

The occurrence of aflatoxin M1 (AFM1) in milk has been widely reported Kenya, with levels freqently exceeding national and international thresholds. Exposure to increases the risk hepatic cancers can also have other negative health impacts children such as growth impairment immunosuppression. Anti-mycotoxin agents (AMAs) included contaminated feeds greatly reduce amount AFM1 released milk. A 45...

In this study, dairy cows were treated with calcium montmorillonite clay (NSP; BASF Corp., Ludwigshaven, Germany) in a replicated 5x5 Latin square design. The primary objectives were to determine if milk composition was altered following ingestion of NSP, and to investigate the ability of NSP to reduce aflatoxin (AF) transfer to milk with the inclusion of low doses in the diet (concentrations e...

Introduction: Aflatoxins, known as causative factors of hepatic and extra-hepatic carcinogenesis within humans, are extremely teratogenic, mutagenic, toxic, and carcinogenic compounds. Materials & Methods: This study was undertaken to determine the occurrence of aflatoxin M1 (AFM1) in 40 raw milk and 47 pasteurized milk samples collected during spring and winter. In order to analyze the samp...

Four dairy goats in the second to third month of lactation were administered [14C]-Aflatoxin B1 ( [14C]-AFB1). Two goats were dosed intravenously (iv) with 130 muCi (182 muCi/mumol) and two were dosed orally with 196 muCi (256 muCi/mumol). Urine, milk and feces were collected for 120 h after [14C]-AFB1 administration. Recoveries (average of two animals) of 14C in urine, milk and feces were, res...

the purpose of this survey was to evaluate natural occurrence and content of aflatoxin m1 (afm1) in dairy products marketed in urmia (iran). during september 2007, 40 samples of pasteurized milk, 40 samples of ultra high temperature treated (uht) milk, 40 samples of creamy cheese and 40 samples of iranian feta cheese were collected from different supermarkets in urmia city. afm1 contents were d...