PURPOSE To evaluate the ocular hypotensive efficacy of 0.05%, 0.1% and 0.25% AR-12286 Ophthalmic Solutions in patients diagnosed with ocular hypertension or glaucoma. DESIGN Parallel comparison, vehicle-controlled, double-masked, 3-week randomized clinical trial. METHODS Subjects (n = 89) with elevated intraocular pressure (IOP) were assigned randomly to receive either 1 of 3 concentrations...

Case history A 58 year old man, diagnosed HIV-1 antibody positive 3 years previously, presented with a 24 hour history of hyperactivity. This culminated in the development of suicidal and homicidal ideation. For fear of injury to himself and others he was admitted to hospital. He had commenced a course of clarithromycin by mouth 500 mg twice daily 10 days previously, for a bacterial chest infec...

The pivotal role of listening comprehension in second/foreign language learning requires that researchers conduct studies which investigate factors that affect test takers’ performances. The present study was set out to examine whether item modality (i.e., written vs. oral items) affects listening comprehension test performance. In addition, it investigated whether allowing test takers to take ...

Background: Recently, exploring novel dietary nondigestible carbohydrates, which are able to influence the gut flora, has drawn much attention. The objective of this study was to find out the effective dose of levan, as a prebiotic, in rats in order to further apply it in the food industry. Methods: Levan at various doses (2-10%) was orally administered to male Wistar Albino rats once a day for...

Sainfoin (Onobrychis viciaefolia Scop.) is adapted to the calcareous soils of the southern Great Plains and can provide early season forage that does not induce bloating; however, little is known about performance by ruminants grazing sainfoin. Our objective was to determine the effect of plant growth stage and grazing pressures on potential animal production from sainfoin as predicted from ene...

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