the first description of an autoimmune encephalitis dates back to 1888, when hermann oppenheim described a patient with neurological symptoms but no underlying brain pathology. the field of autoimmune encephalitides associated with antibodies targeting cell-surface antigens is rapidly expanding and new antibodies are discovered frequently. autoimmune encephalitis is a difficult clinical diagnos...

Every man desires to live long, but no man would be old. Understanding frailty—the concept of vulnerability to adverse health outcomes of people of the same chronological age—continues to motivate research by geriatricians, epidemiologists, sociologists and laboratory-based scientists. While some clinicians have embraced frailty as the Holy Grail of geriatric medicine [1] or advocated it as ano...

Posttraumatic stress disorder (PTSD) occurs following exposure to potentially traumatic experiences such as those regularly encountered by emergency service workers (police, ambulance and firemen/women) and servicemen/women. PTSD is associated with high rates of somatic comorbidities including metabolic syndrome contributing to an excess mortality rate due to preventable cardiovascular diseases...

The internal structure of a molecule can be presented in terms of intra-molecular (i.e., inter atomic)and inter-molecular energies such as van der Waals, bond and bending, torsion, and inversion energy.In this study, changes in molecular energies of individual asphalt components are evaluated as afunction of physical aging factors. The factors for physical aging such as temperature and pressure...

INTRODUCTION Although withdrawal processes form a key motivational basis for cigarette use, smoking cessation treatments appear to exert only modest effects on withdrawal. One treatment option for further reducing withdrawal severity would be to provide smokers with withdrawal regulation training. The objective of this study was to pilot a smoking cessation intervention comprising withdrawal ex...